HDAC-IN-56
Modify Date: 2024-09-16 09:54:11
HDAC-IN-56 structure
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Common Name | HDAC-IN-56 | ||
|---|---|---|---|---|
| CAS Number | 2814571-89-4 | Molecular Weight | 485.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H28FN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HDAC-IN-56HDAC-IN-56 ((S)-17b) is an orally active class I histone deacetylase (HDAC) inhibitor with IC50 values of 56.0 ± 6.0, 90.0 ± 5.9, 422.2 ± 105.1, >10000 nM for HDAC1, HDAC2, HDAC3, and HDAC4-11, respectively. HDAC-IN-56 has potent inhibitory activity while strongly increasing intracellular levels of acetylhistone H3 and P21 and effectively inducing G1 cell cycle arrest and apoptosis.HDAC-IN-56 has antitumor activity [1]. |
| Name | HDAC-IN-56 |
|---|
| Description | HDAC-IN-56 ((S)-17b) is an orally active class I histone deacetylase (HDAC) inhibitor with IC50 values of 56.0 ± 6.0, 90.0 ± 5.9, 422.2 ± 105.1, >10000 nM for HDAC1, HDAC2, HDAC3, and HDAC4-11, respectively. HDAC-IN-56 has potent inhibitory activity while strongly increasing intracellular levels of acetylhistone H3 and P21 and effectively inducing G1 cell cycle arrest and apoptosis.HDAC-IN-56 has antitumor activity [1]. |
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| Related Catalog | |
| Target |
HDAC1:56.0 nM (IC50) HDAC2:90.0 nM (IC50) HDAC3:422.2 nM (IC50) |
| References |
| Molecular Formula | C28H28FN5O2 |
|---|---|
| Molecular Weight | 485.55 |