FPR2 agonist 3

Modify Date: 2026-08-06 11:42:59

FPR2 agonist 3 structure	Common Name	FPR2 agonist 3
	CAS Number	2829263-19-4	Molecular Weight	446.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₀F₂N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FPR2 agonist 3

FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway[1].

Name	FPR2 agonist 3

Description	FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Jie Zang, et al. Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors. J Med Chem. 2023.

Molecular Formula	C₂₅H₂₀F₂N₄O₂
Molecular Weight	446.45

Name: Induction of NO production in Sprague-Dawley rat primary microglial cells at 0.1 uM i...
Source: ChEMBL
Target: Microglia
External Id: CHEMBL5160988

Name: Induction of TNF-alpha production in mouse N9 cells at 0.5 to 5 uM incubated for 24 h...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5160991

Name: Induction of IL-1beta production in mouse N9 cells at 0.5 to 5 uM incubated for 24 hr...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5160985

Name: Neuroprotective activity against Sprague-Dawley rat primary microglial cells assessed...
Source: ChEMBL
Target: Microglia
External Id: CHEMBL5160984

Name: Metabolic stability in rat liver microsomes assessed as compound remaining at 10 uM p...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5160987

Name: Neuroprotective activity against Sprague-Dawley rat primary microglial cells assessed...
Source: ChEMBL
Target: Microglia
External Id: CHEMBL5160986

Name: Cytoprotective activity against LPS-induced cell death in mouse N9 cells assessed as ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5160983

Name: Cytotoxicity against mouse N9 cells assessed as reduction in cell viability by measur...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5160982

Name: Ratio of drug concentration in brain to plasma in CD-1 mouse at 10 mg/kg, ip measured...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5161029

Name: Drug concentration in CD-1 mouse brain at 10 mg/kg, ip measured after 8 hrs by UPLC a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5161028

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FPR2 agonist 3

Use of FPR2 agonist 3

Names

FPR2 agonist 3 Biological Activity

Chemical & Physical Properties

FPR2 agonist 3Bioassay

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.