FK962
Modify Date: 2024-01-09 14:28:51
FK962 structure
|
Common Name | FK962 | ||
|---|---|---|---|---|
| CAS Number | 283167-06-6 | Molecular Weight | 264.295 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 474.4±40.0 °C at 760 mmHg | |
| Molecular Formula | C14H17FN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 240.7±27.3 °C | |
Use of FK962FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions[1]. |
| Name | N-(1-Acetyl-4-piperidinyl)-4-fluorobenzamide |
|---|---|
| Synonym | More Synonyms |
| Description | FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions[1]. |
|---|---|
| Related Catalog | |
| Target |
Somatostatin release[1] |
| In Vitro | FK962 (1 nM-1 μM) significantly enhances high K+-evoked somatostatin release from rat hippocampal slices. FK962 also significantly reduces somatostatin-induced inhibition of Ca2+ channels at 1-100 nM in single rat hippocampal neurons using whole-cell patch-clamp[1]. |
| In Vivo | FK962 (0.1, 0.3 or 1.0 mg/kg; i.p.) and Donepezil (a single dose of 1 mg/kg) act synergistically to improve cognition in rats: as an add-on therapy for Alzheimer's disease[2]. Animal Model: Male Lister Hooded rats, weighing approximately 270-300[2] Dosage: 0.1, 0.3 or 1.0 mg/kg; Donepezil was given as a single dose of 1 mg/kg Administration: Administered i.p. Result: Resulted in minimal cognition enhancement when given separately. Combination showed a significantly greater effect on cognition. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 474.4±40.0 °C at 760 mmHg |
| Molecular Formula | C14H17FN2O2 |
| Molecular Weight | 264.295 |
| Flash Point | 240.7±27.3 °C |
| Exact Mass | 264.127411 |
| LogP | 1.59 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.557 |
| N-(1-Acetyl-4-piperidinyl)-4-fluorobenzamide |
| N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide |
| Benzamide, N-(1-acetyl-4-piperidinyl)-4-fluoro- |
| MFCD09832545 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: FK962
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: FK962
- Price: $550.0/100mg $850.0/250mg $1700.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: FK962
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-(1-acetyl-4-piperidinyl)-4-fluoro-Benzamide
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: ￥2200/5 mg
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