D-Mannitol-13C6

Modify Date: 2024-01-11 10:07:43

D-Mannitol-13C6 Structure
D-Mannitol-13C6 structure
Common Name D-Mannitol-13C6
CAS Number 287112-34-9 Molecular Weight 188.12800
Density N/A Boiling Point N/A
Molecular Formula C6H14O6 Melting Point 167-170ºC(lit.)
MSDS N/A Flash Point N/A

 Use of D-Mannitol-13C6


D-Mannitol-13C6 is the 13C labeled D-Mannitol[1]. D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator[2][3][4].

 Names

Name d-[ul-13c6]mannitol

 D-Mannitol-13C6 Biological Activity

Description D-Mannitol-13C6 is the 13C labeled D-Mannitol[1]. D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator[2][3][4].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Tan, K., et al., The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem, 2009. 284(52): p. 36670-9.  

[3]. Nishiyama, A., et al., Mannitol lowers fat digestibility and body fat accumulation in both normal and cecectomized rats. J Nutr Sci Vitaminol (Tokyo), 2009. 55(3): p. 242-51.  

[4]. Hanieh, H. and E. Sakaguchi, Effect of D-mannitol on feed digestion and cecotrophic system in rabbits. Anim Sci J, 2009. 80(2): p. 157-62.  

 Chemical & Physical Properties

Melting Point 167-170ºC(lit.)
Molecular Formula C6H14O6
Molecular Weight 188.12800
Exact Mass 188.09900
PSA 121.38000
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