EP12

Modify Date: 2024-01-11 18:03:48

EP12 Structure
EP12 structure
Common Name EP12
CAS Number 2882916-73-4 Molecular Weight 427.47
Density N/A Boiling Point N/A
Molecular Formula C26H22FN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EP12


EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth[1].

 Names

Name EP12

 EP12 Biological Activity

Description EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth[1].
Related Catalog
References

[1]. Yao R, et al. Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling. Exp Cell Res. 2023 Oct 1;431(1):113759.  

 Chemical & Physical Properties

Molecular Formula C26H22FN3O2
Molecular Weight 427.47