Anti-inflammatory agent 41

Modify Date: 2024-04-06 11:33:57

Anti-inflammatory agent 41 Structure
Anti-inflammatory agent 41 structure
Common Name Anti-inflammatory agent 41
CAS Number 2896204-90-1 Molecular Weight 543.57
Density N/A Boiling Point N/A
Molecular Formula C33H25N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Anti-inflammatory agent 41


Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].

 Names

Name Anti-inflammatory agent 41

 Anti-inflammatory agent 41 Biological Activity

Description Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].
Related Catalog
In Vitro Anti-inflammatory agent 41 (13a) 显著减少了LPS诱导的p65在J774A.1巨噬细胞中的核转位。
References

[1]. Jun Yang, et al. Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis. Eur J Med Chem. 2023 Mar 5;249:115144.  

 Chemical & Physical Properties

Molecular Formula C33H25N3O5
Molecular Weight 543.57
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