Seleno-DL-cystine

Modify Date: 2024-01-06 15:12:06

Seleno-DL-cystine structure	Common Name	Seleno-DL-cystine
	CAS Number	2897-21-4	Molecular Weight	334.09
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₁₂N₂O₄Se₂	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

Use of Seleno-DL-cystine

Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].

Name	(R,R)-3,3'-diselenobis-(2-aminopropionic acid)
Synonym	More Synonyms

Description	Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: Anti-cancer[1]
References	[1]. Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046.

Molecular Formula	C₆H₁₂N₂O₄Se₂
Molecular Weight	334.09
Exact Mass	335.91300
PSA	126.64000
Vapour Pressure	5.12E-13mmHg at 25°C
Storage condition	-20°C

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H301 + H331-H373-H410
Precautionary Statements	P261-P273-P301 + P310-P311-P501
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T+
Risk Phrases	23/25-33-50/53
Safety Phrases	20/21-28-45-60-61
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3.0
RTECS	AY6031000
HS Code	2922499990

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Bioaccessibility of selenium, selenomethionine and selenocysteine from foods and influence of heat processing on the same.

Food Chem. 194 , 1293-9, (2015)

Selenium (Se) is an essential nutrient with diverse physiological functions. The selenium content of commonly consumed cereals, pulses and green leafy vegetables (GLV) was determined. Bioaccessibility...

Effects of selenium on development, survival, and accumulation in the honeybee (Apis mellifera L.).

Environ. Toxicol. Chem. 32(11) , 2584-92, (2013)

Apis mellifera L. (Hymenoptera: Apidae) is an important agricultural pollinator in the United States and throughout the world. In areas of selenium (Se) contamination, honeybees may be at risk because...

Selenocystine induces reactive oxygen species–mediated apoptosis in human cancer cells

Biomed. Pharmacother. 63(2) , 105-13, (2009)

Epidemiological and clinical studies have demonstrated that dietary supplementation of selenium (Se) could reduce the incidence of human cancers. In this study, selenocystine, a nutritionally availabl...

seleno-dl-cystine

alanine,3,3'-diselenobis-