IT-603

Modify Date: 2025-08-25 17:37:59

IT-603 Structure
IT-603 structure
 Common Name IT-603
CAS Number 292168-90-2 Molecular Weight 329.168
Density N/A Boiling Point N/A
Molecular Formula C11H9BrN2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IT-603


A small molecule inhibitor of the NF-κB family member c-Rel with IC50 of 3 uM in EMSA assays; inhibits human diffuse large B-cell lymphoma (DLBCL) cell line with IC50 of 18 uM, binds c-Rel directly and changes the conformation of the protein, inhibiting DNA binding and transcriptional activity.

 Names

Name IT-603

 IT-603 Biological Activity

Description A small molecule inhibitor of the NF-κB family member c-Rel with IC50 of 3 uM in EMSA assays; inhibits human diffuse large B-cell lymphoma (DLBCL) cell line with IC50 of 18 uM, binds c-Rel directly and changes the conformation of the protein, inhibiting DNA binding and transcriptional activity.
References References 1. Shono Y, et al. Cancer Discov. 2014 May;4(5):578-91. View Related Products by Target NF-κB

 Chemical & Physical Properties

Molecular Formula C11H9BrN2O3S
Molecular Weight 329.168
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Chemsrc provides IT-603(CAS#:292168-90-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of IT-603 are included as well.>> amp version: IT-603

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