Ack1 inhibitor 1

Modify Date: 2025-08-21 23:34:09

Ack1 inhibitor 1 structure	Common Name	Ack1 inhibitor 1
	CAS Number	2924415-92-7	Molecular Weight	727.77
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₉H₄₀F₃N₇O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ack1 inhibitor 1

Ack1 inhibitor 1 is a potent, selective, and orally active inhibitor of ACK1 kinase with an IC50 value of 2.1 nM. Ack1 inhibitor 1 inhibits the phosphorylation of ACK1 and activation of downstream AKT. Ack1 inhibitor 1 has anti-tumor activity[1].

Name	Ack1 inhibitor 1

Description	Ack1 inhibitor 1 is a potent, selective, and orally active inhibitor of ACK1 kinase with an IC50 value of 2.1 nM. Ack1 inhibitor 1 inhibits the phosphorylation of ACK1 and activation of downstream AKT. Ack1 inhibitor 1 has anti-tumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Ack1 Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Li Q, et al. Design, Synthesis, and Evaluation of (R)-8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3-d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor. J Med Chem. 2023 May 25;66(10):6905-6921.

Molecular Formula	C₃₉H₄₀F₃N₇O₄
Molecular Weight	727.77

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Ack1 inhibitor 1

Use of Ack1 inhibitor 1

Names

Ack1 inhibitor 1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.