BChE/HDAC6-IN-1

Modify Date: 2025-08-25 11:17:20

BChE/HDAC6-IN-1 structure	Common Name	BChE/HDAC6-IN-1
	CAS Number	2925457-27-6	Molecular Weight	601.74
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₄₃N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BChE/HDAC6-IN-1

BChE/HDAC6-IN-1 is a potent and selective dual BChE/HDAC6 inhibitor with IC50 values of 4 and 8.9 nM, respectively. BChE/HDAC6-IN-1 ameliorates the cognitive impairment in an Aβ1–42-induced mouse model and has the potental for AD research[1].

Name	BChE/HDAC6-IN-1

Description	BChE/HDAC6-IN-1 is a potent and selective dual BChE/HDAC6 inhibitor with IC50 values of 4 and 8.9 nM, respectively. BChE/HDAC6-IN-1 ameliorates the cognitive impairment in an Aβ1–42-induced mouse model and has the potental for AD research[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Research Areas >> Neurological Disease Signaling Pathways >> Epigenetics >> HDAC Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Lei Wang, ET AL. Design, Synthesis, and Proof of Concept of Balanced Dual Inhibitors of Butyrylcholinesterase (BChE) and Histone Deacetylase 6 (HDAC6) for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2023 Sep 6;14(17):3226-3248.

Molecular Formula	C₃₄H₄₃N₅O₅
Molecular Weight	601.74
InChIKey	SXQWWCZAJUYHPA-UHFFFAOYSA-N
SMILES	CCN(CC)Cc1ccccc1CNC(=O)c1cccc(NC(=O)c2cccc(NC(=O)CCCCCCC(=O)NO)c2)c1

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BChE/HDAC6-IN-1

Use of BChE/HDAC6-IN-1

Names

BChE/HDAC6-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.