USP1-IN-6

Modify Date: 2024-02-04 12:59:17

Use of USP1-IN-6

USP1-IN-6 (compound 11) is a USP1 inhibitor (IC50<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC50 <50 nM[1].

Name	USP1-IN-6

Description	USP1-IN-6 (compound 11) is a USP1 inhibitor (IC50<50 nM). USP1-IN-5 also inhibits MDA-MB-436 cells with IC50 <50 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase
Target	IC50: <50 nM (USP1)[1]
References	[1]. Wu J, et al. Preparation of heteroaromatic compounds as small molecule inhibitors of ubiquitin specific protease 1 (USP1) and uses thereof. World Intellectual Property Organization, WO2023083285 A1. 2023-05-19.

Molecular Formula	C₂₉H₂₇F₃N₈O
Molecular Weight	560.57