Antiproliferative agent-32

Modify Date: 2025-09-08 18:06:01

Antiproliferative agent-32 Structure
Antiproliferative agent-32 structure
Common Name Antiproliferative agent-32
CAS Number 2925814-05-5 Molecular Weight 289.33
Density N/A Boiling Point N/A
Molecular Formula C19H15NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antiproliferative agent-32


Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].

 Names

Name Antiproliferative agent-32

 Antiproliferative agent-32 Biological Activity

Description Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].
Related Catalog
References

[1]. Wang Y, et al. Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria. Eur J Med Chem. 2023 Aug 5;256:115420.  

 Chemical & Physical Properties

Molecular Formula C19H15NO2
Molecular Weight 289.33
InChIKey CSFOTWLIOCUFBI-ZHACJKMWSA-N
SMILES CC(=O)Oc1ccccc1C=Cc1nccc2ccccc12
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