Antiproliferative agent-32

Modify Date: 2025-09-08 18:06:01

Antiproliferative agent-32 structure	Common Name	Antiproliferative agent-32
	CAS Number	2925814-05-5	Molecular Weight	289.33
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₅NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Antiproliferative agent-32

Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].

Name	Antiproliferative agent-32

Description	Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Wang Y, et al. Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria. Eur J Med Chem. 2023 Aug 5;256:115420.

Molecular Formula	C₁₉H₁₅NO₂
Molecular Weight	289.33
InChIKey	CSFOTWLIOCUFBI-ZHACJKMWSA-N
SMILES	CC(=O)Oc1ccccc1C=Cc1nccc2ccccc12

Name: Induction of cell cycle arrest in human Huh-7 cells assessed as decrease in CDK1 expr...
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL5371602

Name: Induction of cell cycle arrest in human Huh-7 cells assessed as decrease in cyclin A ...
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL5371603

Name: Induction of cell cycle arrest in human Huh-7 cells assessed as increase in accumulat...
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL5371600

Name: Induction of cell cycle arrest in human SK-HEP1 cells assessed as decrease in accumul...
Source: ChEMBL
Target: SK-HEP1
External Id: CHEMBL5371601

Name: Antiproliferative activity against human Huh-7 cells assessed as reduction in ratio o...
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL5371598

Name: Antiproliferative activity against human SK-HEP1 cells assessed as reduction in ratio...
Source: ChEMBL
Target: SK-HEP1
External Id: CHEMBL5371599

Name: Inhibition of colony formation in human Huh-7 cells assessed as reduction in number o...
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL5371596

Name: Inhibition of colony formation in human SK-HEP1 cells assessed as reduction in number...
Source: ChEMBL
Target: SK-HEP1
External Id: CHEMBL5371597

Name: Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell g...
Source: ChEMBL
Target: Huh-7
External Id: CHEMBL5371594

Name: Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell...
Source: ChEMBL
Target: SK-HEP1
External Id: CHEMBL5371595

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Antiproliferative agent-32

Use of Antiproliferative agent-32

Names

Antiproliferative agent-32 Biological Activity

Chemical & Physical Properties

Antiproliferative agent-32Bioassay

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.