TS-IN-2

Modify Date: 2024-04-06 11:00:28

TS-IN-2 Structure
TS-IN-2 structure
Common Name TS-IN-2
CAS Number 2945983-00-4 Molecular Weight 377.46
Density N/A Boiling Point N/A
Molecular Formula C18H23N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TS-IN-2


TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].

 Names

Name TS-IN-2

 TS-IN-2 Biological Activity

Description TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].
Related Catalog
References

[1]. Syed Nazreen, et al. New Natural Eugenol Derivatives as Antiproliferative Agents: Synthesis, Biological Evaluation, and Computational Studies. ACS Omega. 2023 May 15;8(21):18811-18822.  

 Chemical & Physical Properties

Molecular Formula C18H23N3O4S
Molecular Weight 377.46