DCLK1-IN-2

Modify Date: 2024-03-08 11:13:18

DCLK1-IN-2 Structure
DCLK1-IN-2 structure
Common Name DCLK1-IN-2
CAS Number 2978517-43-8 Molecular Weight 536.65
Density N/A Boiling Point N/A
Molecular Formula C26H32N8O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DCLK1-IN-2


DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3  nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency[1].

 Names

Name DCLK1-IN-2

 DCLK1-IN-2 Biological Activity

Description DCLK1-IN-2 (compound I-5) is a potent DCLK1 inhibitor with an IC50 of 171.3  nM. DCLK1-IN-2 shows remarkable antiproliferative effects on SW1990 cell lines (IC50 of 0.6 μM) and in vivo antitumor potency[1].
Related Catalog
References

[1]. Yuepeng Chen, et al. Design, synthesis and biological evaluation of novel DCLK1 inhibitor containing purine skeleton for the treatment of pancreatic cancer. European Journal of Medicinal Chemistry. 7 October 2023, 115846.

 Chemical & Physical Properties

Molecular Formula C26H32N8O3S
Molecular Weight 536.65