cinnarizine structure
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Common Name | cinnarizine | ||
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CAS Number | 298-57-7 | Molecular Weight | 368.514 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 509.2±38.0 °C at 760 mmHg | |
Molecular Formula | C26H28N2 | Melting Point | 117-120ºC | |
MSDS | Chinese USA | Flash Point | 229.8±14.6 °C |
Use of cinnarizineCinnarizine is an antihistamine and a calcium channel blocker, promote cerebral blood flow, used to treat cerebral apoplexy, post-trauma cerebral symptoms, and cerebral arteriosclerosis. |
Name | cinnarizine |
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Synonym | More Synonyms |
Description | Cinnarizine is an antihistamine and a calcium channel blocker, promote cerebral blood flow, used to treat cerebral apoplexy, post-trauma cerebral symptoms, and cerebral arteriosclerosis. |
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Related Catalog |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 509.2±38.0 °C at 760 mmHg |
Melting Point | 117-120ºC |
Molecular Formula | C26H28N2 |
Molecular Weight | 368.514 |
Flash Point | 229.8±14.6 °C |
Exact Mass | 368.225250 |
PSA | 6.48000 |
LogP | 4.63 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.626 |
Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xn |
Risk Phrases | R20/22 |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 2 |
RTECS | TL3430000 |
HS Code | 2933599090 |
~79% cinnarizine CAS#:298-57-7 |
Literature: RSC Advances, , vol. 3, # 43 p. 20708 - 20718 |
~75% cinnarizine CAS#:298-57-7 |
Literature: Journal of the American Chemical Society, , vol. 134, # 51 p. 20613 - 20616 |
HS Code | 2933599090 |
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Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Iron oxide induced enhancement of mucoadhesive potential of Eudragit RLPO: formulation, evaluation and optimization of mucoadhesive drug delivery system.
Expert Opin. Drug Deliv. 10(9) , 1179-91, (2013) The objective of the study was to investigate the effect of iron oxide in the development of mucoadhesive tablets of cinnarizine using Eudragit RLPO polymer. A simplex lattice design was employed for ... |
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A combination turbidity and supernatant microplate assay to rank-order the supersaturation limits of early drug candidates.
J. Pharm. Sci. 103(10) , 3022-32, (2014) A unique opportunity exists at the drug discovery stage to overcome inherently poor solubility by selecting drug candidates with superior supersaturation propensity. Existing supersaturation assays co... |
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Factors influencing crystal growth rates from undercooled liquids of pharmaceutical compounds.
J. Phys. Chem. B 118(33) , 9974-82, (2014) Amorphous forms of drugs are increasingly being used to deliver poorly water-soluble compounds. Therefore, understanding the magnitude and origin of differences in crystallization kinetics is highly i... |
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