Potassium Gluconate

Modify Date: 2026-07-23 11:29:59

Potassium Gluconate Structure
Potassium Gluconate structure
 Common Name Potassium Gluconate
CAS Number 299-27-4 Molecular Weight 234.246
Density 1.73 g/cm3 Boiling Point 673.6ºC at 760 mmHg
Molecular Formula C6H11KO7 Melting Point 183 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 375.2ºC

 Use of Potassium Gluconate


Potassium Gluconate (Potassium D-gluconate) is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name Potassium gluconate
Synonym More Synonyms

 Potassium Gluconate Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Potassium Gluconate (Potassium D-gluconate) is an orally active carboxylic acid by the oxidation with antiseptic and chelating properties[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Potassium Gluconate, a simple sugar acid, is the most significant antifungal metabolite produced by Pseudomonas. str. AN5 against the take-all fungal pathogen in biocontrol protection[1].
References

[1]. Kaur R, et al. Gluconic acid: an antifungal agent produced by Pseudomonas species in biological control of take-all. Phytochemistry. 2006 Mar;67(6):595-604.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.73 g/cm3
Boiling Point 673.6ºC at 760 mmHg
Melting Point 183 °C (dec.)(lit.)
Molecular Formula C6H11KO7
Molecular Weight 234.246
Flash Point 375.2ºC
Exact Mass 234.014191
PSA 141.28000
InChIKey HLCFGWHYROZGBI-JJKGCWMISA-M
SMILES O=C([O-])C(O)C(O)C(O)C(O)CO.[K+]
Storage condition room temp

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ5230000
CHEMICAL NAME :
Gluconic acid, monopotassium salt, D-
CAS REGISTRY NUMBER :
299-27-4
LAST UPDATED :
199701
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C6-H11-O7.K
MOLECULAR WEIGHT :
234.27
WISWESSER LINE NOTATION :
Q1YQYQYQYQVO &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10380 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - sleep Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,810,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2664 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,810,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
9650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,810,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
9100 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - sleep Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,810,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2333 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,810,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,810,1972 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
358 gm/kg/32D-I
TOXIC EFFECTS :
Nutritional and Gross Metabolic - changes in potassium Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Related to Chronic Data - death
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,998,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1456 gm/kg/26W-I
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,1043,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
358 gm/kg/32D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - death
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,998,1972
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1456 gm/kg/26W-I
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 6,1043,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80489 No. of Facilities: 2945 (estimated) No. of Industries: 4 No. of Occupations: 14 No. of Employees: 17170 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80489 No. of Facilities: 234 (estimated) No. of Industries: 4 No. of Occupations: 14 No. of Employees: 7786 (estimated) No. of Female Employees: 2416 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS LZ5230000
HS Code 2918160000

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  1

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2918160000
Summary 2918160000. gluconic acid, its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles67

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

CaMKII Controls Whether Touch Is Painful.

J. Neurosci. 35 , 14086-102, (2015)

The sensation of touch is initiated when fast conducting low-threshold mechanoreceptors (Aβ-LTMRs) generate impulses at their terminals in the skin. Plasticity in this system is evident in the process...

[Item 232--Facial dermatoses: acne].

Ann. Dermatol. Venereol. 139(11 Suppl) , A192-6, (2012)

CIEL*a*b* parameters of white dehydrated grapes as quality markers according to chemical composition, volatile profile and mechanical properties.

Anal. Chim. Acta 732 , 105-13, (2012)

In the oenological sector, the withering process is of particular importance in the production of dry and sweet dessert wines due to the total or partial use of overripe and/or dehydrated grapes. This...

 Potassium GluconateBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
Name: qHTS assay to identify small molecule antagonists of the peroxisome proliferator-acti...
Source: 824
Target: N/A
External Id: PPARGV841
Name: qHTS assay to identify small molecule agonists of the TGF-beta/Smad signaling pathway...
Source: 824
Target: N/A
External Id: TGF788
Name: qHTS assay to identify small molecule antagonists of the TGF-beta/Smad signaling path...
Source: 824
Target: N/A
External Id: TGF602
Name: qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell fr...
Source: 824
Target: N/A
External Id: SPEC167MG
Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
Name: qHTS assay to identify small molecule agonists of the peroxisome proliferator-activat...
Source: 824
Target: N/A
External Id: PPARDV813
Name: qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free...
Source: 824
Target: N/A
External Id: SPEC167MR
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
Name: qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells
Source: 824
Target: N/A
External Id: SPEC167CG
Total 186, Current Page 1 of 19
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Monopotassium D-gluconate
potassium (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
kok
kaon
D-Gluconic acid, potassium salt (1:1)
Potassium Gluconate
k-iao
potassium saccharate
EINECS 206-074-2
Katrin
potalium
Kalimozan
Gluconic Acid Potassium Salt
Potassium gluconate (JAN/USP)
Tumil K
D-Gluconic acid potassium salt
Gluconic acid,potassium salt
potasoral
D-Gluconic acid, monopotassium salt
MFCD00064211
Potassium D-gluconate
D-Gluconic Acid, Potassium Salt
Potassium Gluconate [USAN:JAN]
katorin
Gluconic acid, monopotassium salt
sirokal

 Potassium Gluconate | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the melting point of Potassium gluconate?
A: Melting point of Potassium gluconate is 183 °C (dec.)(lit.).
Q: What is the polar surface area (PSA) of Potassium gluconate?
A: Polar surface area (PSA) of Potassium gluconate is 141.28000.
Q: What is the safety information for Potassium gluconate?
A: Safety information for Potassium gluconate: S24/25.
Q: What is the molecular weight of Potassium gluconate?
A: Molecular weight of Potassium gluconate is 234.246.
Q: What are the storage conditions for Potassium gluconate?
A: Storage conditions for Potassium gluconate: room temp.
Q: What is the boiling point of Potassium gluconate?
A: Boiling point of Potassium gluconate is 673.6ºC at 760 mmHg.
Q: What is the English name of Potassium gluconate?
A: The English name of Potassium gluconate is Potassium gluconate.
Q: What is the SMILES notation of Potassium gluconate?
A: SMILES notation of Potassium gluconate is O=C([O-])C(O)C(O)C(O)C(O)CO.[K+].
Q: What is the InChIKey of Potassium gluconate?
A: InChIKey of Potassium gluconate is HLCFGWHYROZGBI-JJKGCWMISA-M.
Q: What is the CAS number of Potassium gluconate?
A: CAS number of Potassium gluconate is 299-27-4.

 Potassium Gluconatefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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Chemsrc provides Potassium Gluconate(CAS#:299-27-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Potassium Gluconate are included as well.>> amp version: Potassium Gluconate

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