NPS ALX Compound 4a

Modify Date: 2025-08-24 02:35:21

NPS ALX Compound 4a Structure
NPS ALX Compound 4a structure
Common Name NPS ALX Compound 4a
CAS Number 299433-10-6 Molecular Weight 431.55
Density N/A Boiling Point N/A
Molecular Formula C25H25N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NPS ALX Compound 4a


NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM, which also has a great binding affinity with Ki of 0.2 nM[1].

 Names

Name NPS ALX Compound 4a dihydrochloride,6-(Hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-1-(1-naphthalenylsulfonyl)-1H-indoledihydrochloride
Synonym More Synonyms

 NPS ALX Compound 4a Biological Activity

Description NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM, which also has a great binding affinity with Ki of 0.2 nM[1].
Related Catalog
Target

IC50: 7.2 nM (5-HT6 receptor) Ki: 0.2 nM (5-HT6 receptor)

References

[1]. Isaac M, et al. 6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindolesderivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21.

 Chemical & Physical Properties

Molecular Formula C25H25N3O2S
Molecular Weight 431.55
Exact Mass 503.12000
PSA 53.93000
LogP 7.00360

 Synonyms

Cyanopindolol hemifumarate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

NPS ALX Compound 4a suppliers


Price: ¥2100/5 mg

Reference only. check more NPS ALX Compound 4a price

Related Compounds: More...