PI3Kα-IN-11

Modify Date: 2024-04-02 20:47:37

PI3Kα-IN-11 Structure
PI3Kα-IN-11 structure
Common Name PI3Kα-IN-11
CAS Number 300803-79-6 Molecular Weight 294.30
Density 1.4±0.1 g/cm3 Boiling Point 622.4±55.0 °C at 760 mmHg
Molecular Formula C17H14N2O3 Melting Point N/A
MSDS N/A Flash Point 330.2±31.5 °C

 Use of PI3Kα-IN-11


PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].

 Names

Name WAY-299017
Synonym More Synonyms

 PI3Kα-IN-11 Biological Activity

Description PI3Kα-IN-11 is a potent PI3Kα inhibitor with anticancer activity[1].
Related Catalog
Target

PI3Kα

References

[1]. Sabbah DA, et al.N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα). Bioorg Med Chem. 2012 Dec 15;20(24):7175-83.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 622.4±55.0 °C at 760 mmHg
Molecular Formula C17H14N2O3
Molecular Weight 294.30
Flash Point 330.2±31.5 °C
Exact Mass 294.100433
LogP 1.04
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.667

 Synonyms

N-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide
N-Benzyl-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxamide
3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-2-oxo-N-(phenylmethyl)-
4-Hydroxy-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid benzylamide