IQP-0528

Modify Date: 2024-01-06 14:31:40

IQP-0528 Structure
IQP-0528 structure
Common Name IQP-0528
CAS Number 301297-45-0 Molecular Weight 340.42
Density N/A Boiling Point N/A
Molecular Formula C20H24N2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IQP-0528


IQP-0528 is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI). IQP-0528 shows nanomolar activity against both HIV-1 and HIV-2, with an HIV-1 EC50 of 0.2 nM and an HIV-2 EC50 of 100 nM[1].

 Names

Name 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-propan-2-ylpyrimidine-2,4-dione
Synonym More Synonyms

 IQP-0528 Biological Activity

Description IQP-0528 is a highly potent nonnucleoside reverse transcriptase inhibitor (NNRTI). IQP-0528 shows nanomolar activity against both HIV-1 and HIV-2, with an HIV-1 EC50 of 0.2 nM and an HIV-2 EC50 of 100 nM[1].
Related Catalog
References

[1]. Su JT, et al. A Dose Ranging Pharmacokinetic Evaluation of IQP-0528 Released from Intravaginal Rings in Non-Human Primates. Pharm Res. 2017;34(10):2163-2171.

 Chemical & Physical Properties

Molecular Formula C20H24N2O3
Molecular Weight 340.42
Exact Mass 340.17900
PSA 72.19000
LogP 3.33010

 Synonyms

1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(propan-2-yl)pyrimidine-2,4(1h,3h)-dione
2,4(1H,3H)-Pyrimidinedione,1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-isopropyl
UNII-1Y42TZL33O
IQP-528
IQP-0528
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