2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol

Modify Date: 2024-01-10 13:04:29

2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol structure	Common Name	2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol
	CAS Number	30199-26-9	Molecular Weight	218.335
	Density	0.9±0.1 g/cm3	Boiling Point	326.9±11.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	147.2±8.9 °C

Use of 2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol

Xanthorrhizol, isolated from Curcuma xanthorrhiza Roxb, is a potential antibacterial agent.

Name	2-methyl-5-[(2R)-6-methylhept-5-en-2-yl]phenol
Synonym	More Synonyms

Description	Xanthorrhizol, isolated from Curcuma xanthorrhiza Roxb, is a potential antibacterial agent.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Natural Products >> Others
In Vitro	Xanthorrhizol is a potential antibacterial agent from Curcuma xanthorrhiza against streptocpccus mutants[1]. SEM analysis shows that, treatment of Candida species with MIC of Xanthorrhizol affects the external morphology of these yeasts. Cells incubated in the presence of Xanthorrhizol demonstrate a greater tendency to clump compared with the control cultures. Xanthorrhizol treated C. glabrata cells shows minor abnormalities without a smooth or a slightly awkward surface. Xanthorrhizol-treated Candida cells exhibit deformation and protrusions on the cell surface, which is more clearly demonstrated with C. guilliermondii and C. parapsilosis. In general, Candida exposed to, Xanthorrhizol at concentrations 1 x MICs exhibits substantial ultrastructural abnormalities such as shape deformation, protrusion, rugged cells surface, and clumping[2].
In Vivo	Ear edema induced by the topical application of TPA is suppressed by pre-treatment with Xanthorrhizol in a doserelated manner (P<0.005). Topical application of Xanthorrhizol alone does not induce ear edema in mice. All the mice treated with 7.5 nM TPA for 19 weeks after initiation by DMBA developed an average of 15.5±2.3 skin tumors per mouse (tumor multiplicity). Pre-treatment with 2 and 6 μM Xanthorrhizol reduces tumor multiplicity to 6.9±1.1 (P<0.005) and 4.0±1.1 (P<0.005), respectively, at 19 weeks. In addition, Xanthorrhizol at 2 and 6 μM dose dependently lowers the percentage of tumor-bearing mice (tumor incidence) to 80 and 57%, respectively, at the termination of the experiments. Furthermore, the tumor multiplicity (P<0.05) and incidence are reduced in the DMBA-initiated mice that are topically treated with Xanthorrhizol for 6 weeks after the induction of papillomas with hyperplasia, mild dysplasia and moderate dysplasia by topical TPA application for 6, 18 and 24 weeks, respectively. The increased ODC expression in mouse epidermis with acute inflammation and tumor promotion induced by TPA is inhibited by pre-treatment with Xanthorrhizol in a dose-dependent manner. The topical application of Xanthorrhizol after the induction of papillomas with hyperplasia and dysplasia also potently inhibited ODC expression[3].
References	[1]. Hwang JK, et al. izol: a potential antibacterial agent from Curcuma xanthorrhiza against Streptococcus mutans. Planta Med. 2000 Mar;66(2):196-7. [2]. YAYA RUKAYADI, et al. The Effects of Xanthorrhizol on the Morphology of Candida Cells. Microbiology Indonesia, 2007,1(2):98-100. [3]. Won Yoon Chung, et al. Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kB. Carcinogenesis vol.28 no.6 pp.1224–1231, 2007.

Density	0.9±0.1 g/cm3
Boiling Point	326.9±11.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₂O
Molecular Weight	218.335
Flash Point	147.2±8.9 °C
Exact Mass	218.167068
PSA	20.23000
LogP	5.48
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.522

Hazard Codes	T
Risk Phrases	R60
Safety Phrases	S45;S53;S36/S37/S39

2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol

2-Methyl-5-[(2R)-6-methylhept-5-en-2-yl]phenol

1,3,5,10-bisabolatetraen-3-ol

Phenol,5-(1,5-dimethyl-4-hexenyl)-2-methyl-,(-)

(R)-xanthorrhizol

(-)-5-(1,5-Dimethyl-4-hexenyl)-2-methylphenol

(R)-5-(1,5-Dimethyl-4-hexenyl)-o-cresol

xanthorrhizol

(R)-5-(1-5-Dimethyl-4-hexenyl)-2-methylphenol

Xanthorrizol

Phenol, 5-(1,5-dimethyl-4-hexenyl)-2-methyl-, (R)-

(R)-(-)-xanthorrizol

Phenol, 5-[(1R)-1,5-dimethyl-4-hexenyl]-2-methyl-

Phenol, 5-[(1R)-1,5-dimethyl-4-hexen-1-yl]-2-methyl-

(1R)-5-(1,5-dimethyl-4-hexenyl)-2-methylphenol

EINECS 250-090-2

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Nanjing Peptide Biotech Ltd
China
Product Name: Xanthorrhizol
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Delivery: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

Get all suppliers and price by the below link:

2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol suppliers

2-Methyl-5-[(2R)-6-methyl-5-hepten-2-yl]phenol price