α-Methyl-5-hydroxytryptamine maleate

Modify Date: 2025-08-24 21:43:57

α-Methyl-5-hydroxytryptamine maleate structure	Common Name	α-Methyl-5-hydroxytryptamine maleate
	CAS Number	304-52-9	Molecular Weight	306.31400
	Density	N/A	Boiling Point	411.7ºC at 760 mmHg
	Molecular Formula	C₁₅H₁₈N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	202.8ºC

Use of α-Methyl-5-hydroxytryptamine maleate

α-Methylserotonin is a potent and selective agonist of 5-HT2 receptor.α-Methylserotonin is an analogue of serotonin formed in vivo from α-methyltryptophan.α-Methylserotonin mediates the lymphatic smooth muscle contraction and prevents the up-regulation of serotonin-receptor-mediated phosphoinositide hydrolysis[1][2][3].

Name	α-Methyl-5-hydroxytryptamine maleate
Synonym	More Synonyms

Description	α-Methylserotonin is a potent and selective agonist of 5-HT2 receptor.α-Methylserotonin is an analogue of serotonin formed in vivo from α-methyltryptophan.α-Methylserotonin mediates the lymphatic smooth muscle contraction and prevents the up-regulation of serotonin-receptor-mediated phosphoinositide hydrolysis[1][2][3].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Dobbins DE. Receptor mechanisms of serotonin-induced prenodal lymphatic constriction in the canine forelimb. Am J Physiol. 1998 Feb;274(2):H650-4. [2]. Brumley MR, et al. The serotonergic agonists quipazine, CGS-12066A, and alpha-methylserotonin alter motor activity and induce hindlimb stepping in the intact and spinal rat fetus. Behav Neurosci. 2005 Jun;119(3):821-33. [3]. Edwards E, et al. (+/-)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane(DOI) and alpha-methyl-5-HT: 5-HT2 receptor agonistic action on phosphatidylinositol metabolism in the rat fronto-cingulate and entorhinal cortex. Neuropharmacology. 1992 Jul;31(7):615-21.

Description

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

References

[1]. Dobbins DE. Receptor mechanisms of serotonin-induced prenodal lymphatic constriction in the canine forelimb. Am J Physiol. 1998 Feb;274(2):H650-4.

[2]. Brumley MR, et al. The serotonergic agonists quipazine, CGS-12066A, and alpha-methylserotonin alter motor activity and induce hindlimb stepping in the intact and spinal rat fetus. Behav Neurosci. 2005 Jun;119(3):821-33.

[3]. Edwards E, et al. (+/-)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane(DOI) and alpha-methyl-5-HT: 5-HT2 receptor agonistic action on phosphatidylinositol metabolism in the rat fronto-cingulate and entorhinal cortex. Neuropharmacology. 1992 Jul;31(7):615-21.

Boiling Point	411.7ºC at 760 mmHg
Molecular Formula	C₁₅H₁₈N₂O₅
Molecular Weight	306.31400
Flash Point	202.8ºC
Exact Mass	306.12200
PSA	136.64000
LogP	2.17530
InChIKey	LYPCGXKCQDYTFV-UHFFFAOYSA-N
SMILES	CC(N)Cc1c[nH]c2ccc(O)cc12

Safety Phrases	22-24/25
WGK Germany	3

(+/-)-5-(benzyl...

CAS#:108477-22-1

α-Methyl-5-hydr...

CAS#:304-52-9

Literature: Ismaiel; Titeler; Miller; Smith; Glennon Journal of medicinal chemistry, 1990 , vol. 33, # 2 p. 755 - 758

Precursor 1
CAS#:108477-22-1 (+/-)-5-(benzyl...
DownStream 0

MFCD00082468

4a-methyl-5-hydroxytryptamine

a-Methyl-5-hydroxytryptaminemaleate

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: α-Methylserotonin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

α-Methyl-5-hydroxytryptamine maleate suppliers

α-Methyl-5-hydroxytryptamine maleate price

α-Methyl-5-hydroxytryptamine maleate

Use of α-Methyl-5-hydroxytryptamine maleate

Names

α-Methyl-5-hydroxytryptamine maleate Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.