N'-benzylpivalohydrazide

Modify Date: 2025-09-13 21:04:48

N'-benzylpivalohydrazide Structure
N'-benzylpivalohydrazide structure
 Common Name N'-benzylpivalohydrazide
CAS Number 306-19-4 Molecular Weight 206.28400
Density 1.015g/cm3 Boiling Point 296.1ºC at 760mmHg
Molecular Formula C12H18N2O Melting Point N/A
MSDS N/A Flash Point 105.6ºC

 Use of N'-benzylpivalohydrazide


Pivalylbenzhydrazine (Pivhydrazine) is a potent monoamine oxidase (MAO) inhibitor. Pivalylbenzhydrazine decreases cartilage growth in normal rats. Pivalylbenzhydrazine can be used in research of depression[1].

 Names

Name N'-benzyl-2,2-dimethylpropanehydrazide
Synonym More Synonyms

 N'-benzylpivalohydrazide Biological Activity

Description Pivalylbenzhydrazine (Pivhydrazine) is a potent monoamine oxidase (MAO) inhibitor. Pivalylbenzhydrazine decreases cartilage growth in normal rats. Pivalylbenzhydrazine can be used in research of depression[1].
Related Catalog
In Vivo Pivalylbenzhydrazine (Pivhydrazine; 5 mg/kg; i.p.; daily, for 5 d; immature female rats) inhibits the growth of the epiphysial cartilage[1]. Animal Model: Immature female rats (40 g, 3-4 weeks age)[1] Dosage: 5 mg/kg Administration: Intraperitoneal injection; daily, for 5 days Result: Inhibited the growth of the epiphysial cartilage

 Chemical & Physical Properties

Density 1.015g/cm3
Boiling Point 296.1ºC at 760mmHg
Molecular Formula C12H18N2O
Molecular Weight 206.28400
Flash Point 105.6ºC
Exact Mass 206.14200
PSA 41.13000
LogP 2.63530
Index of Refraction 1.517

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TO7874000
CHEMICAL NAME :
Pivalic acid, 2-benzylhydrazide
CAS REGISTRY NUMBER :
306-19-4
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H18-N2-O
MOLECULAR WEIGHT :
206.32
WISWESSER LINE NOTATION :
1X1&1&VMM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>280 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
10 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 5,343,1968

 Safety Information

RIDADR UN 3249
Packaging Group III
Hazard Class 6.1(b)
HS Code 2928000090

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

Tersavide
Pivazid
N'-benzyl-2,2-dimethyl-propanehydrazide
N'-benzylpivalohydrazide
Betamezide
N-Benzyl pivalhydrazide
Pivalylbenzhydrazine
1-Trimethylacetyl-2-benzyl-hydrazin
Tersavid
PIVHYDRAZINE
Pivalyl benzylhydrazine
Pivaloylbenzylhydrazine
Betamezid
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