spermine tetrahydrochloride
spermine tetrahydrochloride structure
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Common Name | spermine tetrahydrochloride | ||
|---|---|---|---|---|
| CAS Number | 306-67-2 | Molecular Weight | 334.157 | |
| Density | 1.01 g/mL at 20 °C | Boiling Point | 308.4ºC at 760mmHg | |
| Molecular Formula | C10H30Cl4N4 | Melting Point | 310-311 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 175.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of spermine tetrahydrochlorideSpermine, a polycationic biogenic polyamine derived from spermidine, may be used in a wide variety of biological applications as a supplement or regulatory agent.Used as co-matrix with DHB for MALDI-MS of sialylated glycans in negative ion mode. |
Summary: Spermine tetrahydrochloride (N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride, CAS: 306-67-2, molecular formula: C10H30Cl4N4, molecular weight: 334.16) is a polyamine of biogenic origin derived from spermidine. It may be used as a supplement or regulatory agent in a wide range of biological applications. Store at 2-8°C. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.01 g/mL at 20 °C |
|---|---|
| Boiling Point | 308.4ºC at 760mmHg |
| Melting Point | 310-311 °C (dec.)(lit.) |
| Molecular Formula | C10H30Cl4N4 |
| Molecular Weight | 334.157 |
| Flash Point | 175.6ºC |
| Exact Mass | 332.106812 |
| PSA | 76.10000 |
| LogP | 5.03380 |
| Appearance of Characters | powder |
| InChIKey | XLDKUDAXZWHPFH-UHFFFAOYSA-N |
| SMILES | Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN |
| Storage condition | 2-8°C |
| Water Solubility | H2O: 1 M at 20 °C, clear, colorless |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | EJ7230000 |
| HS Code | 2921290000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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spermine tetrah... CAS#:306-67-2 |
| Literature: Synthetic Communications, , vol. 32, # 16 p. 2441 - 2452 |
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~%
spermine tetrah... CAS#:306-67-2 |
| Literature: Synthetic Communications, , vol. 32, # 16 p. 2441 - 2452 |
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~%
spermine tetrah... CAS#:306-67-2 |
| Literature: Synthetic Communications, , vol. 32, # 16 p. 2441 - 2452 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 1 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2921290000 |
|---|---|
| Summary | 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Interaction of myo-inositol hexakisphosphate with biogenic and synthetic polyamines.
Org. Biomol. Chem. 13 , 7500-12, (2015) Within all the eukaryotic cells myo-inositol phosphates (InsPs) are an important group of biomolecules that are potentially related to signaling functions. The most abundant member of this family in n... |
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An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution.
Anal. Sci. 31 , 721-4, (2015) This study is the first to report on the detection of biogenic amines in an aqueous solution using an organic field-effect transistor (OFET) device with an extended gate electrode modified with a laye... |
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Effect of Novel Starter Culture on Reduction of Biogenic Amines, Quality Improvement, and Sensory Properties of Doenjang, a Traditional Korean Soybean Fermented Sauce Variety.
J. Food Sci. 80 , M1794-803, (2015) To select appropriate microorganisms as starter cultures for the reliable and reproducible fermentation of soybean fermented products of Korean Doenjang, various ratios of fungi (Aspergillus oryzae J,... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of [14C]spermidine uptake at polyamine transport system in mouse L1210 cel...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1285750
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Name: Ratio of spermidine Km to compound Ki for polyamine transport system in mouse L1210 c...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1285751
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Name: Small-molecule inhibitors of ST2 (IL1RL1)
Source: 20881
Target: interleukin-1 receptor-like 1 isoform [homo sapiens]
External Id: ST2_IL33_Inhibitors_Primary_Screening_77700
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Name: qHTS assay for measurement of the activity of small molecule inhibitors on Zika virus...
Source: NCGC
Target: N/A
External Id: ZIK097
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Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
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Name: 96-well format Chlamydomonas reinhardtii Algae Gravitaxis Assay to measure the differ...
Source: University of Pittsburgh Molecular Library Screening Center
Target: N/A
External Id: MH081217, Chlamydomonas reinhardtii Gravitaxis Assay to Identify Small Molecule Inhibitors of Cilia.
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Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
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Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
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Name: qHTS assay to identify small molecule antagonists of the estrogen related receptor (E...
Source: 824
Target: N/A
External Id: ERR513
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| N,N'-Bis(3-aMinopropyl)-1,4-butanediaMine Tetrahydrochloride |
| EINECS 206-189-8 |
| N1,N1'-(Butane-1,4-diyl)bis(propane-1,3-diamine) tetrahydrochloride |
| Spermine tetrahydrochloride |
| N-(2-Aminoethyl)-N'-(3-aminopropyl)-1,4-butanediamine tetrahydrochloride |
| 1,5,10,14-tetraazoniatetradecane tetrachloride |
| Additive Screening |
| Spermine hydrochloride |
| Geontine Tetrahydrochloride |
| Spermine tetrahydrochloride 0.1 M |
| 1,4-Butanediamine, N-(2-aminoethyl)-N-(3-aminopropyl)-, hydrochloride (1:4) |
| Musculamine tetrahydrochloride |
| MFCD00012914 |
| Neuridine tetrahydrochloride |
| Spm tetrahydrochloride |
| Gerontine tetrahydrochloride |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: The English name of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride. |
| Q: What is the InChIKey of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: InChIKey of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is XLDKUDAXZWHPFH-UHFFFAOYSA-N. |
| Q: What are the storage conditions for N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: Storage conditions for N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride: 2-8°C. |
| Q: What is the SMILES notation of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: SMILES notation of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is Cl.Cl.Cl.Cl.NCCCNCCCCNCCCN. |
| Q: What is the molecular weight of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: Molecular weight of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is 334.157. |
| Q: What are the uses of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: Main uses of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride: Spermine, a polycationic biogenic polyamine derived from spermidine, may be used in a wide variety of biological applications as a supplement or regulatory agent.Used as co-matrix with DHB for MALDI-MS of sialylated glycans in negative ion mode. |
| Q: What is the CAS number of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: CAS number of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is 306-67-2. |
| Q: What is the melting point of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: Melting point of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is 310-311 °C (dec.)(lit.). |
| Q: What is the safety information for N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: Safety information for N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride: S26-S36. |
| Q: What is the LogP of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride? |
| A: LogP of N,N'-bis(3-aminopropyl)butane-1,4-diamine,tetrahydrochloride is 5.03380. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |