Withanolide

Modify Date: 2026-07-15 11:04:43

Withanolide Structure
Withanolide structure
Common Name Withanolide
CAS Number 30655-48-2 Molecular Weight 470.598
Density 1.3±0.1 g/cm3 Boiling Point 663.7±55.0 °C at 760 mmHg
Molecular Formula C28H38O6 Melting Point N/A
MSDS N/A Flash Point 220.3±25.0 °C

 Names

Name withanolide D
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 663.7±55.0 °C at 760 mmHg
Molecular Formula C28H38O6
Molecular Weight 470.598
Flash Point 220.3±25.0 °C
Exact Mass 470.266846
PSA 96.36000
LogP 2.89
Vapour Pressure 0.0±4.6 mmHg at 25°C
Index of Refraction 1.600
InChIKey SASUFNRGCZMRFD-JCUIILOWSA-N
SMILES CC1=C(C)C(=O)OC(C(C)(O)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC32C)C1

 Synthetic Route

 WithanolideBioassay

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Name: Ratio of induction of heat shock response in GFP-tagged human 293T cells to IC50 for ...
Source: ChEMBL
Target: HEK-293T
External Id: CHEMBL4255619
Name: Antiproliferative activity against human MM1.S cells assessed as reduction in cell vi...
Source: ChEMBL
Target: MM1.S
External Id: CHEMBL4830670
Name: Induction of heat shock response in GFP-tagged human 293T cells after overnight incub...
Source: ChEMBL
Target: HEK-293T
External Id: CHEMBL4255618
Name: Antiproliferative activity against human RPMI 8226 cells assessed as reduction in cel...
Source: ChEMBL
Target: RPMI-8226
External Id: CHEMBL4830669
Name: Antiproliferative activity against human MM1.R cells assessed as reduction in cell vi...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4830668
Name: Antiproliferative activity against human RPMI-8226 cells cultured as 3D-spheroids ass...
Source: ChEMBL
Target: RPMI-8226
External Id: CHEMBL4830667
Name: Cytotoxicity against human 293T cells assessed as reduction in cell viability at 1 to...
Source: ChEMBL
Target: HEK-293T
External Id: CHEMBL4255615
Name: Induction of heat shock response in GFP-tagged human 293T cells at 1 uM after overnig...
Source: ChEMBL
Target: HEK-293T
External Id: CHEMBL4255614
Name: Inhibition of TNF-alpha stimulated NF-KappaB in human HEK293 cells transfected with N...
Source: ChEMBL
Target: Nuclear factor NF-kappa-B p100 subunit
External Id: CHEMBL4830671
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 Synonyms

(4β,5β,6β,22R)-4,20-Dihydroxy-5,6:22,26-diepoxyergosta-2,24-diene-1,26-dione
WITHANOLIDE D(P)
Withanolide D
Withanolide
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