3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE

Modify Date: 2024-01-15 16:15:35

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Structure
3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE structure
Common Name 3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE
CAS Number 306935-14-8 Molecular Weight 246.33100
Density 1.238g/cm3 Boiling Point 415.9ºC at 760mmHg
Molecular Formula C12H14N4S Melting Point 91-93ºC
MSDS USA Flash Point 205.3ºC

 Names

Name 3-phenyl-5-piperazin-1-yl-1,2,4-thiadiazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.238g/cm3
Boiling Point 415.9ºC at 760mmHg
Melting Point 91-93ºC
Molecular Formula C12H14N4S
Molecular Weight 246.33100
Flash Point 205.3ºC
Exact Mass 246.09400
PSA 69.29000
LogP 2.00850
Index of Refraction 1.609

 MSDS

Name: 3-Phenyl-5-piperazino-1 2 4-thiadiazole 97% Material Safety Data Sheet
Synonym:
CAS: 306935-14-8
Section 1 - Chemical Product MSDS Name:3-Phenyl-5-piperazino-1 2 4-thiadiazole 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
306935-14-8 3-Phenyl-5-piperazino-1,2,4-thiadiazol 97% unlisted
Hazard Symbols: C
Risk Phrases: 34

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Causes burns.Air sensitive.
Potential Health Effects
Eye:
Causes eye burns.
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes chemical burns to the respiratory tract.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Do not induce vomiting. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Corrosives area. Store under nitrogen.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 306935-14-8: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 91 - 93 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H14N4S
Molecular Weight: 246

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, halogens, halogenated agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 306935-14-8 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-Phenyl-5-piperazino-1,2,4-thiadiazole - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.*
Hazard Class: 8
UN Number: 3259
Packing Group: III
IMO
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 3259
Packing Group: III
RID/ADR
Shipping Name: AMINES, SOLID, CORROSIVE, N.O.S.
Hazard Class: 8
UN Number: 3259
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: C
Risk Phrases:
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 306935-14-8: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 306935-14-8 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 306935-14-8 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes C: Corrosive;
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39
HS Code 2934999090

 Synthetic Route

~98%

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Structure

3-PHENYL-5-PIPE...

CAS#:306935-14-8

Literature: Kono, Mitsunori; Matsumoto, Takahiro; Kawamura, Toru; Nishimura, Atsushi; Kiyota, Yoshihiro; Oki, Hideyuki; Miyazaki, Junichi; Igaki, Shigeru; Behnke, Craig A.; Shimojo, Masato; Kori, Masakuni Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 1 p. 28 - 41

~%

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Structure

3-PHENYL-5-PIPE...

CAS#:306935-14-8

Literature: US2007/4741 A1, ; Page/Page column 13 ;

~49%

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Structure

3-PHENYL-5-PIPE...

CAS#:306935-14-8

Literature: Keith, John M.; Apodaca, Richard; Xiao, Wei; Seierstad, Mark; Pattabiraman, Kanaka; Wu, Jiejun; Webb, Michael; Karbarz, Mark J.; Brown, Sean; Wilson, Sandy; Scott, Brian; Tham, Chui-Se; Luo, Lin; Palmer, James; Wennerholm, Michelle; Chaplan, Sandra; Breitenbucher, J. Guy Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 17 p. 4838 - 4843

~%

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Structure

3-PHENYL-5-PIPE...

CAS#:306935-14-8

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 1 p. 28 - 41

~%

3-PHENYL-5-PIPERAZINO-1,2,4-THIADIAZOLE Structure

3-PHENYL-5-PIPE...

CAS#:306935-14-8

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 1 p. 28 - 41

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Phenyl-5-piperazino-1,2,4-thiadiazole
3-phenyl-5-(piperazin-1-yl)-1,2,4-thiadiazole
1-(3-Phenyl-1,2,4-thiadiazol-5-yl)piperazine
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