Zalypsis

Modify Date: 2025-08-25 17:10:38

Zalypsis structure	Common Name	Zalypsis
	CAS Number	308359-57-1	Molecular Weight	709.71
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₇H₃₈F₃N₃O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Zalypsis

Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks[1][2].

Name	Zalypsis

Description	Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Duan Z, et al. Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines. Cancer Chemother Pharmacol. 2009 May;63(6):1121-9. [2]. Petek BJ, et al. PM00104 (Zalypsis®): a marine derived alkylating agent. Molecules. 2014 Aug 15;19(8):12328-35.

Description

Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks[1][2].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

References

[1]. Duan Z, et al. Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines. Cancer Chemother Pharmacol. 2009 May;63(6):1121-9.

[2]. Petek BJ, et al. PM00104 (Zalypsis®): a marine derived alkylating agent. Molecules. 2014 Aug 15;19(8):12328-35.