Aloesin

Modify Date: 2024-01-03 14:59:58

Aloesin Structure
Aloesin structure
Common Name Aloesin
CAS Number 30861-27-9 Molecular Weight 394.373
Density 1.5±0.1 g/cm3 Boiling Point 628.0±55.0 °C at 760 mmHg
Molecular Formula C19H22O9 Melting Point N/A
MSDS N/A Flash Point 224.2±25.0 °C

 Use of Aloesin


Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].

 Names

Name 7-hydroxy-5-methyl-2-(2-oxopropyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one
Synonym More Synonyms

 Aloesin Biological Activity

Description Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].
Related Catalog
References

[1]. Zhang LQ, et al. Aloesin Suppresses Cell Growth and Metastasis in Ovarian Cancer SKOV3 Cells through the Inhibition of the MAPK Signaling Pathway. Anal Cell Pathol (Amst). 2017;2017:8158254.

[2]. Wahedi HM, et al. Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo. Phytomedicine. 2017 May 15;28:19-26.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 628.0±55.0 °C at 760 mmHg
Molecular Formula C19H22O9
Molecular Weight 394.373
Flash Point 224.2±25.0 °C
Exact Mass 394.126373
PSA 157.66000
LogP 0.64
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.637
Storage condition -20℃

 Synthetic Route

~%

Aloesin Structure

Aloesin

CAS#:30861-27-9

Literature: CSIR, BIO/CHEMTEK Patent: WO2006/97811 A1, 2006 ; Location in patent: Page/Page column 5; 8-10 ;

 Synonyms

Aloe resin B
4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-
Aloersin B
(1S)-1,5-Anhydro-1-[7-hydroxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-chromen-8-yl]-D-glucitol
D-Glucitol, 1,5-anhydro-1-C-[7-hydroxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-1-benzopyran-8-yl]-, (1S)-
Aloesin
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  • Purity: 98.0%
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