VU590 structure
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Common Name | VU590 | ||
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CAS Number | 313505-85-0 | Molecular Weight | 488.53 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C24H32N4O7 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of VU590VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney[1][2]. |
Name | 7,13-bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane,dihydrochloride |
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Synonym | More Synonyms |
Description | VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney[1][2]. |
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Related Catalog | |
Target |
IC50: 290 nM (Kir1.1), 8 μM (Kir7.1)[1] |
References |
Molecular Formula | C24H32N4O7 |
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Molecular Weight | 488.53 |
Exact Mass | 560.18000 |
PSA | 125.81000 |
LogP | 5.39680 |
VU 590 dihydrochloride |