Retro 1
Modify Date: 2025-08-25 15:26:12
Retro 1 structure
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Common Name | Retro 1 | ||
|---|---|---|---|---|
| CAS Number | 313683-81-7 | Molecular Weight | 373.244 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 544.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C18H17BrN2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 282.9±30.1 °C | |
Use of Retro 1Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge. |
| Name | 7-Bromo-5-phenyl-4-propionyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one |
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| Synonym | More Synonyms |
| Description | Retro 1 is the first small molecule inhibitor of plant toxin ricin, protects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Golgi network) interface; has no effect on endogenous retrograde cargo proteins; protects mice against ricin challenge. |
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| References | References 1. Stechmann B, et al. Cell. 2010 Apr 16;141(2):231-42. View Related Products by Target Other Targets |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 544.1±50.0 °C at 760 mmHg |
| Molecular Formula | C18H17BrN2O2 |
| Molecular Weight | 373.244 |
| Flash Point | 282.9±30.1 °C |
| Exact Mass | 372.047333 |
| LogP | 3.35 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.604 |
| 2H-1,4-Benzodiazepin-2-one, 7-bromo-1,3,4,5-tetrahydro-4-(1-oxopropyl)-5-phenyl- |
| MFCD00807208 |
| 7-Bromo-5-phenyl-4-propionyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one |