DSHN

Modify Date: 2024-09-13 19:44:07

DSHN Structure
DSHN structure
Common Name DSHN
CAS Number 313952-63-5 Molecular Weight 323.36
Density 1.4±0.1 g/cm3 Boiling Point 519.7±60.0 °C at 760 mmHg
Molecular Formula C15H17NO5S Melting Point N/A
MSDS N/A Flash Point 268.1±32.9 °C

 Use of DSHN


DSHN is a potent small heterodimer partner (SHP) activator. DSHN inhibits Ccl2 expression and secretion by inhibiting p65 activation of Ccl2 promoter activity. DSHN can be used in research of cancer[1].

 Names

Name DSHN
Synonym More Synonyms

 DSHN Biological Activity

Description DSHN is a potent small heterodimer partner (SHP) activator. DSHN inhibits Ccl2 expression and secretion by inhibiting p65 activation of Ccl2 promoter activity. DSHN can be used in research of cancer[1].
Related Catalog
References

[1]. Yang Z, et, al. A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2. Mol Cancer Ther. 2016 Oct;15(10):2294-2301.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 519.7±60.0 °C at 760 mmHg
Molecular Formula C15H17NO5S
Molecular Weight 323.36
Flash Point 268.1±32.9 °C
Exact Mass 323.082733
LogP 3.49
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.634

 Synonyms

5-[(Diethylamino)sulfonyl]-3-hydroxy-2-naphthalenecarboxylic acid
DSHN
2-Naphthalenecarboxylic acid, 5-[(diethylamino)sulfonyl]-3-hydroxy-
5-(diethylsulfamoyl)-3-hydroxy-2-naphthalenecarboxylic acid
5-(Diethylsulfamoyl)-3-hydroxy-2-naphthoic acid
5-(DIETHYLSULFAMOYL)-3-HYDROXYNAPHTHALENE-2-CARBOXYLIC ACID