N-CHLOROACETYLISONIPECOTIC ACID

Modify Date: 2023-01-17 01:44:38

N-CHLOROACETYLISONIPECOTIC ACID Structure
N-CHLOROACETYLISONIPECOTIC ACID structure
Common Name N-CHLOROACETYLISONIPECOTIC ACID
CAS Number 318280-69-2 Molecular Weight 205.64
Density 1.349g/cm3 Boiling Point 406.2ºC at 760 mmHg
Molecular Formula C8H12ClNO3 Melting Point 109-111ºC
MSDS N/A Flash Point 199.4ºC

 Use of N-CHLOROACETYLISONIPECOTIC ACID


MurA-IN-4 has antibacterial activity and is a MurA inhibitor that inhibits bacterial cell wall synthesis[1].

 Names

Name 1-(2-chloroacetyl)piperidine-4-carboxylic acid
Synonym More Synonyms

 N-CHLOROACETYLISONIPECOTIC ACID Biological Activity

Description MurA-IN-4 has antibacterial activity and is a MurA inhibitor that inhibits bacterial cell wall synthesis[1].
Related Catalog
References

[1]. Grabrijan K, et al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Dec 5;243:114752.  

 Chemical & Physical Properties

Density 1.349g/cm3
Boiling Point 406.2ºC at 760 mmHg
Melting Point 109-111ºC
Molecular Formula C8H12ClNO3
Molecular Weight 205.64
Flash Point 199.4ºC
Exact Mass 205.05100
PSA 57.61000
LogP 0.48630
Index of Refraction 1.526

 Safety Information

Risk Phrases R36/37/38
Safety Phrases S26-S36/37/39
HS Code 2933399090

 Synthetic Route

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N-CHLOROACETYLISONIPECOTIC ACID Structure

N-CHLOROACETYLI...

CAS#:318280-69-2

Literature: US6569854 B1, ;

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

N-Chloroacetylisonipecotic acid
1-(2-CHLOROACETYL)-4-PIPERIDINECARBOXYLIC ACID
1-chloroacetylpiperidine-4-carboxylic acid
MFCD02093986