3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane

Modify Date: 2024-01-06 20:12:01

3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane Structure
3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane structure
Common Name 3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane
CAS Number 31865-25-5 Molecular Weight 219.236
Density 1.305±0.06 g/cm3 Boiling Point 353.9±42.0 °C at 760 mmHg
Molecular Formula C12H13NO3 Melting Point N/A
MSDS N/A Flash Point 167.8±27.9 °C

 Names

Name benzyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.305±0.06 g/cm3
Boiling Point 353.9±42.0 °C at 760 mmHg
Molecular Formula C12H13NO3
Molecular Weight 219.236
Flash Point 167.8±27.9 °C
Exact Mass 219.089539
PSA 42.07000
LogP 1.32
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.596
Water Solubility Very slightly soluble (0.48 g/L) (25 ºC)

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Synthetic Route

~99%

3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane Structure

3-Cbz-6-oxa-3-a...

CAS#:31865-25-5

Literature: Pfizer Inc Patent: US2005/256310 A1, 2005 ; Location in patent: Page/Page column 12 ;

~95%

3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane Structure

3-Cbz-6-oxa-3-a...

CAS#:31865-25-5

Literature: NYCOMED GMBH; BARTELS, Bjoern; WEINBRENNER, Steffen; MARX, Degenhard; DIEFENBACH, Joerg; DUNKERN, Torsten; MENGE, Wiro M.P.B.; CHRISTIAANS, Johannes A. M. Patent: WO2010/15588 A1, 2010 ; Location in patent: Page/Page column 94 ; WO 2010/015588 A1

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3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane Structure

3-Cbz-6-oxa-3-a...

CAS#:31865-25-5

Literature: Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer; Kaga, Harumi Tetrahedron Letters, 2004 , vol. 45, # 43 p. 8057 - 8059

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3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane Structure

3-Cbz-6-oxa-3-a...

CAS#:31865-25-5

Literature: Kamal, Ahmed; Shaik, Ahmad Ali; Sandbhor, Mahendra; Malik, M. Shaheer; Kaga, Harumi Tetrahedron Letters, 2004 , vol. 45, # 43 p. 8057 - 8059

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3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane Structure

3-Cbz-6-oxa-3-a...

CAS#:31865-25-5

Literature: NOVARTIS AG; BARSANTI, Paul, A.; HU, Cheng; JIN, Xianming; NG, Simon, C.; PFISTER, Keith, B.; SENDZIK, Martin; SUTTON, James Patent: WO2012/101064 A1, 2012 ; WO 2012/101064 A1

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-benzyloxycarbonyl-3,4-epoxypyrrolidine
3-Cbz-6-oxa-3-aza-bicyclo[3.1.0]hexane
3,4-epoxy-1-carbobenzyloxy-pyrrolidine
Benzyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate
6-Oxa-3-azabicyclo[3.1.0]hexane-3-carboxylic acid, phenylmethyl ester
N-benzyloxycarbonyl-3,4-epoxy-pyrrolidine
3-Aza-6-oxabicyclo[3.1]hexane-3-carboxylic acid benzyl ester
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