L-Selenomethionine

Modify Date: 2024-01-02 21:35:51

L-Selenomethionine Structure
L-Selenomethionine structure
 Common Name L-Selenomethionine
CAS Number 3211-76-5 Molecular Weight 196.106
Density N/A Boiling Point 320.8±37.0 °C at 760 mmHg
Molecular Formula C5H11NO2Se Melting Point 265 °C
MSDS Chinese USA Flash Point 147.8±26.5 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09		 Signal Word Danger

 Use of L-Selenomethionine


L-SelenoMethionine is a major natural food-form of selenium.Target：The median lethal dose (LD50) of L-SelenoMethionine in rats given an intraperitoneal injection was determined to 4.25 mg Se/kg body and thus is comparable to that of selenite or selenate. In mice, the LD50 of L-SelenoMethionine was 8.8 ± 1.37 mg Se/kg, and the minimal lethal dose, 4.0 mg Se/kg, after intravenous injection.

 Names

Name L-selenomethionine
Synonym More Synonyms

 L-Selenomethionine Biological Activity

Description L-SelenoMethionine is a major natural food-form of selenium.Target：The median lethal dose (LD50) of L-SelenoMethionine in rats given an intraperitoneal injection was determined to 4.25 mg Se/kg body and thus is comparable to that of selenite or selenate. In mice, the LD50 of L-SelenoMethionine was 8.8 ± 1.37 mg Se/kg, and the minimal lethal dose, 4.0 mg Se/kg, after intravenous injection.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Schrauzer GN, et al. Selenomethionine: a review of its nutritional significance, metabolism and toxicity. J Nutr. 2000 Jul;130(7):1653-1656.

 Chemical & Physical Properties

Boiling Point 320.8±37.0 °C at 760 mmHg
Melting Point 265 °C
Molecular Formula C5H11NO2Se
Molecular Weight 196.106
Flash Point 147.8±26.5 °C
Exact Mass 196.995499
PSA 63.32000
LogP -0.65
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 18 ° (C=0.5, 2mol/L HCl)
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EK7713840
CHEMICAL NAME :
Butanoic acid, 2-amino-4-(methylseleno)-, (S)-
CAS REGISTRY NUMBER :
3211-76-5
LAST UPDATED :
199707
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H11-N-O2-Se

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
269 mg/kg/8W-C
TOXIC EFFECTS :
Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JTEMEM Journal of Trace Elements in Experimental Medicine. (Wiley-Liss, Inc., 605 Third Ave., New York, NY 10158-0012) V.1- 1988- Volume(issue)/page/year: 4,69,1991

 Safety Information

Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger
Hazard Statements H301 + H331-H373-H410
Precautionary Statements Missing Phrase - N15.00950417-P260-P304 + P340 + P312-P403 + P233
Hazard Codes T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases R23/25;R33;R50/53
Safety Phrases S20/21-S28-S45-S60-S61-S28A
RIDADR UN 3283 6.1/PG 2
WGK Germany 3
RTECS EK7713840
Packaging Group I; II; III
Hazard Class 6.1
HS Code 2922499990

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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 Synonyms

L-Selenomethioninum
(2S)-2-Amino-4-(methylseleno)butanoic acid
(S)-2-Amino-4-(Methylseleno)Butyric Acid
MFCD00037210
(2S)-2-Amino-4-(methylselanyl)butanoic acid
Selenium-L-methionine
Se-methionine
SeMet
L-selenomethionine zwitterion
(S)-2-Amino-4-(methylselanyl)butanoic acid
Seleno-L-methionine
(2S)-2-amino-4-methylselanylbutanoic acid
Butanoic acid, 2-amino-4-(methylseleno)-, (2S)-
L(+)-Selenomethionine
(S)-2-Amino-4-(methylseleno)butanoic acid
L-SelenoMethionine
L-(+)-Selenomethionine
Selenomethionine
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