(2H8)-2,2'-Bipyridine

Modify Date: 2024-01-06 18:02:06

(2H8)-2,2'-Bipyridine Structure
(2H8)-2,2'-Bipyridine structure
Common Name (2H8)-2,2'-Bipyridine
CAS Number 32190-42-4 Molecular Weight 164.233
Density 1.1±0.1 g/cm3 Boiling Point 272.5±0.0 °C at 760 mmHg
Molecular Formula C10D8N2 Melting Point 70-73ºC(lit.)
MSDS Chinese USA Flash Point 107.2±12.0 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of (2H8)-2,2'-Bipyridine


2,2′-Bipyridine-d8 is the deuterium labeled 2,2′-Bipyridine-d8[1].

 Names

Name 2,3,4,5-tetradeuterio-6-(3,4,5,6-tetradeuteriopyridin-2-yl)pyridine
Synonym More Synonyms

 (2H8)-2,2'-Bipyridine Biological Activity

Description 2,2′-Bipyridine-d8 is the deuterium labeled 2,2′-Bipyridine-d8[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 272.5±0.0 °C at 760 mmHg
Melting Point 70-73ºC(lit.)
Molecular Formula C10D8N2
Molecular Weight 164.233
Flash Point 107.2±12.0 °C
Exact Mass 164.118958
PSA 25.78000
LogP 1.28
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.581

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements P261-P301 + P310-P305 + P351 + P338
Hazard Codes T: Toxic;
Risk Phrases 25-36/37/38
Safety Phrases 26-45
RIDADR UN 2811 6.1/PG 3

 Synthetic Route

~89%

(2H8)-2,2'-Bipyridine Structure

(2H8)-2,2'-Bipy...

CAS#:32190-42-4

Literature: Matsubara, Seijiro; Asano, Keisuke; Kajita, Yuichi; Yamamoto, Mitsuru Synthesis, 2007 , # 13 p. 2055 - 2059

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(2H8)-2,2'-Bipyridine Structure

(2H8)-2,2'-Bipy...

CAS#:32190-42-4

Literature: Cook, Michael J.; Lewis, Anthony P.; McAuliffe, Glenn S. G.; Skarda, Vladimir; Thomson, Andrew J.; et. al. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 8 p. 1293 - 1302

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2,2 inverted exclamation marka-Bipyridyl-d8
(H)-2,2'-Bipyridine
Perdeuteriated 2,2'-bipyridyl
2,2 inverted exclamation marka-Dipyridyl-d8
2,2'-Dipyridyl-d8
perdeuterio 2,2'-bipyridine
2,2'-Bipyridine-d
2,2'-DIMERCAPTO-4,4',6,6'-TETRAHYDROXYPYRIMIDINO-5,5'-PENTAMETHINEOXONOLE
2,2'-Bipyridyl-d8
MFCD00190432
2,2'-bipyridine-d8
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