SCH 221510
Modify Date: 2024-01-02 19:37:24
SCH 221510 structure
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Common Name | SCH 221510 | ||
|---|---|---|---|---|
| CAS Number | 322473-89-2 | Molecular Weight | 397.55 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H31NO | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SCH 221510SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC50 of 12 nM and Ki of 0.3 nM. SCH 221510 shows an anxiolytic-like effect[1]. |
| Name | 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol |
|---|---|
| Synonym | More Synonyms |
| Description | SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC50 of 12 nM and Ki of 0.3 nM. SCH 221510 shows an anxiolytic-like effect[1]. |
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| Related Catalog | |
| Target |
EC50: 12 nM (NOP)[1] |
| References |
| Molecular Formula | C28H31NO |
|---|---|
| Molecular Weight | 397.55 |
| Exact Mass | 397.24100 |
| PSA | 23.47000 |
| LogP | 5.84530 |
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SCH 221510 CAS#:322473-89-2 |
| Literature: Ho, Ginny D.; Anthes, John; Bercovici, Ana; Caldwell, John P.; Cheng, Kuo-Chi; Cui, Xiaoming; Fawzi, Ahmad; Fernandez, Xiomara; Greenlee, William J.; Hey, John; Korfmacher, Walter; Lu, Sherry X.; McLeod, Robbie L.; Ng, Fay; Torhan, April Smith; Tan, Zheng; Tulshian, Deen; Varty, Geoffrey B.; Xu, Xiaoying; Zhang, Hongtao Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 9 p. 2519 - 2523 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| MM 77 dihydrochloride |
| 3-Endo-8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol |
| SCH 221510 |