2-HYDROXY-2-ISOPROPYLSUCCINIC ACID
2-HYDROXY-2-ISOPROPYLSUCCINIC ACID structure
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Common Name | 2-HYDROXY-2-ISOPROPYLSUCCINIC ACID | ||
|---|---|---|---|---|
| CAS Number | 3237-44-3 | Molecular Weight | 176.16700 | |
| Density | 1.342g/cm3 | Boiling Point | 306.4ºC at 760mmHg | |
| Molecular Formula | C7H12O5 | Melting Point | 144-146ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 153.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 2-HYDROXY-2-ISOPROPYLSUCCINIC ACIDα-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-isopropylmalic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1]. |
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| Related Catalog | |
| In Vitro | α-Isopropylmalate (500 μM) increases LEU3 protein (Leu3p)-dependent transcription[1]. α-Isopropylmalate (10 mM, 48 h) increases reporter gene expression in preadipocytes (30A5)[2]. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.342g/cm3 |
|---|---|
| Boiling Point | 306.4ºC at 760mmHg |
| Melting Point | 144-146ºC(lit.) |
| Molecular Formula | C7H12O5 |
| Molecular Weight | 176.16700 |
| Flash Point | 153.3ºC |
| Exact Mass | 176.06800 |
| PSA | 94.83000 |
| InChIKey | BITYXLXUCSKTJS-UHFFFAOYSA-N |
| SMILES | CC(C)C(O)(CC(=O)O)C(=O)O |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2918199090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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2-HYDROXY-2-ISO... CAS#:3237-44-3
Learn More
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| Literature: Tetrahedron Letters, , vol. 21, # 27 p. 2657 - 2660 |
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2-HYDROXY-2-ISO... CAS#:3237-44-3
Learn More
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| Literature: Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1787 - 1792 |
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2-HYDROXY-2-ISO... CAS#:3237-44-3
Learn More
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| Literature: Nishida, Ritsuo; Kim, Chul-Sa; Fukami, Hiroshi; Irie, Ryozo Agricultural and Biological Chemistry, 1991 , vol. 55, # 7 p. 1787 - 1792 |
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2-HYDROXY-2-ISO... CAS#:3237-44-3 |
| Literature: Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1787 - 1792 |
|
~%
2-HYDROXY-2-ISO... CAS#:3237-44-3 |
| Literature: Agricultural and Biological Chemistry, , vol. 55, # 7 p. 1787 - 1792 |
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2-HYDROXY-2-ISO... CAS#:3237-44-3 |
| Literature: Journal of Organic Chemistry, , vol. 23, p. 835 |
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2-HYDROXY-2-ISO... CAS#:3237-44-3 |
| Literature: Journal of Organic Chemistry, , vol. 23, p. 835 |
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2-HYDROXY-2-ISO... CAS#:3237-44-3 |
| Literature: Tetrahedron Letters, , vol. 21, # 27 p. 2657 - 2660 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
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| DownStream 2 | |
CAS#:563-80-4
CAS#:124-38-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2918199090 |
|---|---|
| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes.
Metabolomics 11 , 1277-1286, (2015) Biomarkers for the development of type 2 diabetes (T2D) are useful for prediction and intervention of the disease at earlier stages. In this study, we performed a longitudinal study of changes in meta... |
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Human metabolic responses to chronic environmental polycyclic aromatic hydrocarbon exposure by a metabolomic approach.
J. Proteome Res. 14 , 2583-93, (2015) The toxicities of polycyclic aromatic hydrocarbons (PAHs) have been extensively explored due to their carcinogenic and mutagenic potency; however, little is known about the metabolic responses to chro... |
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A potential tool for diagnosis of male infertility: Plasma metabolomics based on GC-MS.
Talanta 147 , 82-9, (2015) Male infertility has become an important public health problem worldwide. Nowadays the diagnosis of male infertility frequently depends on the results of semen quality or requires more invasive surgic... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 2-hydroxy-2-isopropyl-succinic acid |
| 2-HYDROXY-2-ISOPROPYLSUCCINIC ACID |
| 2-Hydroxy-2-isopropyl-bernsteinsaeure |
| MFCD00075003 |
| 2-Hydroxy-2-isopropylbutanedioic acid |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of 2-isopropylmalic acid? |
| A: Melting point of 2-isopropylmalic acid is 144-146ºC(lit.). |
| Q: What are the upstream materials of 2-isopropylmalic acid? |
| A: Related upstream materials(CAS) of 2-isopropylmalic acid: 72213-98-0;136997-61-0;137782-07-1;118897-65-7;29509-06-6. |
| Q: What is the boiling point of 2-isopropylmalic acid? |
| A: Boiling point of 2-isopropylmalic acid is 306.4ºC at 760mmHg. |
| Q: What is the safety information for 2-isopropylmalic acid? |
| A: Safety information for 2-isopropylmalic acid: 26-37/39. |
| Q: What are the downstream products of 2-isopropylmalic acid? |
| A: Related downstream products(CAS) of 2-isopropylmalic acid: 563-80-4;124-38-9. |
| Q: What are the uses of 2-isopropylmalic acid? |
| A: Main uses of 2-isopropylmalic acid: α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast[1]. |
| Q: What is the polar surface area (PSA) of 2-isopropylmalic acid? |
| A: Polar surface area (PSA) of 2-isopropylmalic acid is 94.83000. |
| Q: What is the InChIKey of 2-isopropylmalic acid? |
| A: InChIKey of 2-isopropylmalic acid is BITYXLXUCSKTJS-UHFFFAOYSA-N. |
| Q: What is the molecular formula of 2-isopropylmalic acid? |
| A: Molecular formula of 2-isopropylmalic acid is C7H12O5. |
| Q: What is the SMILES notation of 2-isopropylmalic acid? |
| A: SMILES notation of 2-isopropylmalic acid is CC(C)C(O)(CC(=O)O)C(=O)O. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |