Lorazepam glucuronide

Modify Date: 2024-01-09 09:41:57

Lorazepam glucuronide Structure
Lorazepam glucuronide structure
Common Name Lorazepam glucuronide
CAS Number 32781-79-6 Molecular Weight 497.28200
Density 1.76g/cm3 Boiling Point 779.5ºC at 760mmHg
Molecular Formula C21H18Cl2N2O8 Melting Point N/A
MSDS N/A Flash Point 425.2ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name Lorazepam glucuronide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.76g/cm3
Boiling Point 779.5ºC at 760mmHg
Molecular Formula C21H18Cl2N2O8
Molecular Weight 497.28200
Flash Point 425.2ºC
Exact Mass 496.04400
PSA 157.91000
LogP 0.59140
Index of Refraction 1.731

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302-H319
Precautionary Statements P210-P305 + P351 + P338
RIDADR UN 1648 3 / PGII

 Articles13

More Articles
Commentary on: Dou C, Bournique J, Zinda M, Gnezda M, Nally A, Salamone S. Comparison of rates of hydrolysis of lorazepam-glucuronide, oxazepam-glucuronide and temazepam-glucuronide catalyzed by E. coli beta-glucuronidase using the on-line benzodiazepine screening immunoassay on the Roche/Hitachi 917 analyzer.

J. Forensic Sci. 47(2) , 427-8, (2002)

Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltration.

Am. J. Kidney Dis. 45(2) , 360-71, (2005)

The objective is to study the population pharmacokinetics of lorazepam and midazolam in critically ill patients with acute renal failure who are treated with continuous venovenous hemofiltration (CVVH...

Biotransformation and excretion of lorazepam in patients with chronic renal failure.

Br. J. Clin. Pharmacol. 3(6) , 1033-9, (1976)

To evaluate the effect of end-stage renal insufficiency and haemodialysis on the elimination of lorazepam, single oral doses of the drug (2.5 mg) were administered to normal subjects and patients with...

 Synonyms

Lorazepam-O-glucuronid
lorazepam acetate