3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE

Modify Date: 2025-09-10 20:52:43

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure
3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE structure
Common Name 3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE
CAS Number 33050-38-3 Molecular Weight 189.00200
Density 1.9g/cm3 Boiling Point N/A
Molecular Formula C5H2Cl2N4 Melting Point 140-143ºC
MSDS N/A Flash Point N/A

 Names

Name 3,6-Dichloro[1,2,4]triazolo[4,3-b]pyridazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.9g/cm3
Melting Point 140-143ºC
Molecular Formula C5H2Cl2N4
Molecular Weight 189.00200
Exact Mass 187.96600
PSA 43.08000
LogP 1.43110
Index of Refraction 1.807
InChIKey YHVQNULRPMZYEO-UHFFFAOYSA-N
SMILES Clc1ccc2nnc(Cl)n2n1

 Safety Information

Hazard Codes Xi: Irritant;

 Synthetic Route

~91%

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure

3,6-DICHLORO-[1...

CAS#:33050-38-3

Literature: GENFIT; BOUROTTE, Maryline; DELHOMEL, Jean-François; DUBERNET, Mathieu; GOUY, Marie-Hélène Patent: WO2013/45519 A1, 2013 ; Location in patent: Page/Page column 43 ;

~48%

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure

3,6-DICHLORO-[1...

CAS#:33050-38-3

Literature: Baloniak, S.; Katrusiak, A. Polish Journal of Chemistry, 1994 , vol. 68, # 4 p. 683 - 692

~40%

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure

3,6-DICHLORO-[1...

CAS#:33050-38-3

Literature: Baloniak, S.; Katrusiak, A. Polish Journal of Chemistry, 1994 , vol. 68, # 4 p. 683 - 692

~10%

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure

3,6-DICHLORO-[1...

CAS#:33050-38-3

Literature: Baloniak, S.; Katrusiak, A. Polish Journal of Chemistry, 1994 , vol. 68, # 4 p. 683 - 692

~%

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure

3,6-DICHLORO-[1...

CAS#:33050-38-3

Literature: Polish Journal of Chemistry, , vol. 68, # 4 p. 683 - 692

~%

3,6-DICHLORO-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZINE Structure

3,6-DICHLORO-[1...

CAS#:33050-38-3

Literature: Polish Journal of Chemistry, , vol. 68, # 4 p. 683 - 692

 Bioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen
Source: NCGC
External Id: tdp43-p2-repeat
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 Synonyms

3,6-dichloro-[1,2,4]triazolo[4,3-b]pyridazine
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