3-[(3-Cholamidopropyl)dimethylamMonio]-1-propanesulfonate hydrate 98

Modify Date: 2024-01-07 15:39:00

3-[(3-Cholamidopropyl)dimethylamMonio]-1-propanesulfonate hydrate 98 Structure
3-[(3-Cholamidopropyl)dimethylamMonio]-1-propanesulfonate hydrate 98 structure
Common Name 3-[(3-Cholamidopropyl)dimethylamMonio]-1-propanesulfonate hydrate 98
CAS Number 331717-45-4 Molecular Weight 632.89
Density N/A Boiling Point N/A
Molecular Formula C32H60N2O8S Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

 Use of 3-[(3-Cholamidopropyl)dimethylamMonio]-1-propanesulfonate hydrate 98


CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution[1][2].

 Names

Name 3-[dimethyl-[3-[[(4R)-4-[(3R,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]propane-1-sulfonate,hydrate
Synonym More Synonyms

  Biological Activity

Description CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution[1][2].
Related Catalog
References

[1]. Kroflic A, et al. Thermodynamic characterization of 3-[(3-cholamidopropyl)-dimethylammonium]-1-propanesulfonate (CHAPS) micellization using isothermal titration calorimetry: temperature, salt, and pH dependence. Langmuir. 2012 Jul 17;28(28):10363-71.  

[2]. Menshikova I, et al. Nucleosomes structure and dynamics: effect of CHAPS. Int J Biochem Mol Biol. 2011;2(2):129-137.  

 Chemical & Physical Properties

Molecular Formula C32H60N2O8S
Molecular Weight 632.89
Exact Mass 632.40700
PSA 168.09000
LogP 4.73890

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger
Hazard Statements H315-H319-H335-H360D
Precautionary Statements P201-P261-P305 + P351 + P338-P308 + P313
RIDADR NONH for all modes of transport

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 Synonyms

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate hydrate,CHAPS