Fluorescein isothiocyanate structure
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Common Name | Fluorescein isothiocyanate | ||
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CAS Number | 3326-32-7 | Molecular Weight | 389.381 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 708.6±60.0 °C at 760 mmHg | |
Molecular Formula | C21H11NO5S | Melting Point | >360 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 382.4±32.9 °C | |
Symbol |
GHS08 |
Signal Word | Danger |
Use of Fluorescein isothiocyanateFITC is a derivative of fluorescein for the labeling of amines. |
Name | fluorescein 5-isothiocyanate |
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Synonym | More Synonyms |
Description | FITC is a derivative of fluorescein for the labeling of amines. |
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Related Catalog | |
In Vitro | Annexin V-FITC/PI is employed to detect chondrocyte apoptosis[1]. The PEI-modified CDs are conjugated with fluorescein isothiocyanate (FITC) to fabricate CDs-FITC composites[2]. |
Cell Assay | The frequency of chondrocyte apoptosis is measured by flow cytometry with Annexin V-fluorescein isothiocyanate (FITC) and propidium iodide. A total of 1×104 treated chondrocytes are collected from each group, washed in cold PBS and incubated with Annexin V-FITC and PI at room temperature for 15 min in the dark on ice. These samples are then analyzed using a fluorescence-activated cell sorter. Cell Quest software is used to analyze the percentage of apoptosis. All tests are repeated in triplicate. |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 708.6±60.0 °C at 760 mmHg |
Melting Point | >360 °C(lit.) |
Molecular Formula | C21H11NO5S |
Molecular Weight | 389.381 |
Flash Point | 382.4±32.9 °C |
Exact Mass | 389.035797 |
PSA | 120.44000 |
LogP | 4.00 |
Vapour Pressure | 0.0±2.3 mmHg at 25°C |
Index of Refraction | 1.754 |
Storage condition | 2-8°C |
Stability | Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids. |
Water Solubility | practically insoluble |
Symbol |
GHS08 |
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Signal Word | Danger |
Hazard Statements | H317-H334 |
Precautionary Statements | P261-P280-P342 + P311 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R22;R36/37/38;R42/43 |
Safety Phrases | S22-S45-S36/37/39-S26-S36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
~% Fluorescein iso... CAS#:3326-32-7 |
Literature: WO2006/84339 A1, ; Page/Page column 30 ; |
~% Fluorescein iso... CAS#:3326-32-7 |
Literature: Tomasch, Miriam; Schwed, J. Stephan; Kuczka, Karina; Meyer Dos Santos, Sascha; Harder, Sebastian; Nuesing, Rolf M.; Paulke, Alexander; Stark, Holger ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 9 p. 774 - 779 |
~% Fluorescein iso... CAS#:3326-32-7 |
Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779 |
~% Fluorescein iso... CAS#:3326-32-7 |
Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779 |
~% Fluorescein iso... CAS#:3326-32-7 |
Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779 |
~% Fluorescein iso... CAS#:3326-32-7 |
Literature: ACS Medicinal Chemistry Letters, , vol. 3, # 9 p. 774 - 779 |
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5-FITC |
Isothiocyanatofluorescein |
5-Isothionatofluorescein |
Benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-isothiocyanato- |
FITC Fluorescein 5-isothiocyanate |
EINECS 248-207-7 |
Fluorescein Isothiosyanate |
fluorescein isothiocyanate isomer 1 |
fluorescein 6-isothiocyanate |
FITC ISOMER |
Fluorescein 5-Isothiocyanate (isomer I) |
3',6'-Dihydroxy-5-isothiocyanato-3H-spiro[2-benzofurane-1,9'-xanthén]-3-one |
5-FITC (isomer I) |
5-Isothiocyanatofluorescein (isomer I) |
FITC |
5-Fluorescein Isothiocyanate |
fluorescein 5-isothiocyanate |
FITC,Fluorescein 5-isothiocyanate |
FITC isomer I |
Fluorescein isothiocyanate,isomer 1 |
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)-5-isothiocyanatobenzoic acid |
Fluorescein Isothiocyanate (isomer I) |
Fluorescein isothiocyanate isomer I |
Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato- |
FITC-I |
Fluorescein 5(6)-isothiocyanate |
Fluorescein-5-isothiocyanate |
MFCD00005063 |
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-5-isothiocyanato- |
Fluorescein Isothiocyanate |
3',6'-Dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one |