2-Chloro-4-hydroxybenzonitrile

Modify Date: 2025-08-26 06:17:20

2-Chloro-4-hydroxybenzonitrile Structure
2-Chloro-4-hydroxybenzonitrile structure
Common Name 2-Chloro-4-hydroxybenzonitrile
CAS Number 3336-16-1 Molecular Weight 153.566
Density 1.4±0.1 g/cm3 Boiling Point 323.2±27.0 °C at 760 mmHg
Molecular Formula C7H4ClNO Melting Point 160ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 149.3±23.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-chloro-4-hydroxybenzonitrile
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 323.2±27.0 °C at 760 mmHg
Melting Point 160ºC (dec.)(lit.)
Molecular Formula C7H4ClNO
Molecular Weight 153.566
Flash Point 149.3±23.7 °C
Exact Mass 152.998138
PSA 44.02000
LogP 2.48
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.611
InChIKey BDDVAWDNVWLHDQ-UHFFFAOYSA-N
SMILES N#Cc1ccc(O)cc1Cl

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases 26-37/39
RIDADR NONH for all modes of transport
WGK Germany 3.0
HS Code 2926909090

 Customs

HS Code 2926909090
Summary HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles2

More Articles
Novel macrocyclic C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents.

Bioorg. Med. Chem. 19(18) , 5468-79, (2011)

Novel macrocyclic C-aryl glucoside SGLT2 inhibitors were designed and synthesized. Two different synthetic routes of macrocyclization were adopted to prepare novel ansa SGLT2 inhibitors. Among the com...

An expeditious synthesis of 6-aminophenanthridines. Gug F, et al.

Tetrahedron Lett. 46(21) , 3725-27, (2005)

 Synonyms

HO(3-Cl,4-CN)Ph
2-Chloro-4-hydroxybenzonitrile
2-chloro-4-hydroxy-benzonitrile
3-chloro-4-cyano phenol
MFCD00052185
2-chloro-4-hydroxybenzenecarbonitrile
2-Chlor-4-hydroxybenzonitril
Benzonitrile, 2-chloro-4-hydroxy-
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