Voacamine

Modify Date: 2024-01-02 11:31:31

Voacamine structure	Common Name	Voacamine
	CAS Number	3371-85-5	Molecular Weight	704.89700
	Density	1.309g/cm3	Boiling Point	N/A
	Molecular Formula	C₄₃H₅₂N₄O₅	Melting Point	223℃
	MSDS	N/A	Flash Point	N/A

Use of Voacamine

Voacamine, an indole alkaloid, isolated from Voacanga Africana, exhibits potent cannabinoid CB1 receptor antagonistic activity[1]. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells[1].

Name	methyl 12-methoxy-13-(17-methoxy-17-oxovobasan-3alpha-yl)ibogamine-18-carboxylate
Synonym	More Synonyms

Description	Voacamine, an indole alkaloid, isolated from Voacanga Africana, exhibits potent cannabinoid CB1 receptor antagonistic activity[1]. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor
References	[1]. Kitajima M, et al. Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1962-4. [2]. Meschini S, et al. Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia, inhibits P-glycoprotein action in multidrug-resistant tumor cells. Int J Oncol. 2005 Dec;27(6):1597-603.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

References

[1]. Kitajima M, et al. Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1962-4.

[2]. Meschini S, et al. Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia, inhibits P-glycoprotein action in multidrug-resistant tumor cells. Int J Oncol. 2005 Dec;27(6):1597-603.

Density	1.309g/cm3
Melting Point	223℃
Molecular Formula	C₄₃H₅₂N₄O₅
Molecular Weight	704.89700
Exact Mass	704.39400
PSA	99.89000
LogP	6.36470
Index of Refraction	1.674
Storage condition	2-8℃

Dodecandisaeure-monomethylester

methyl hydrogen dodecanedioate

monomethyl-dodecanedioate

epi-Voacamin

methyl ester of 1,12-dodecanedioic acid,dimethyl ester

Dodecanedioic acid monomethyl ester

11MeOCO undec acid

Voacamine

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Voacamine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Voacamine
Price: ￥2948.0/20mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 12-Methoxy-13-((3alpha)-17-methoxy-17-oxovobasan-3-yl)ibogamine-18-carboxylic acid methyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥3360/5 mg

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Voacamine

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