9-hydroxystearic acid
Modify Date: 2024-02-02 17:55:19
9-hydroxystearic acid structure
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Common Name | 9-hydroxystearic acid | ||
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| CAS Number | 3384-24-5 | Molecular Weight | 300.48 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H36O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 9-hydroxystearic acid9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity[1]. |
| Name | 9-hydroxyoctadecanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | 9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity[1]. |
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| Related Catalog | |
| Target |
HDAC1 |
| In Vitro | 9-Hydroxyoctadecanoic acid (9-HSA) 可以结合到人 HDAC1 蛋白三维模型的活性位点[1]。 9-Hydroxyoctadecanoic acid (9-HSA) (100 μM; 24 h) 抑制 HT29 细胞增殖，诱导 G0/G1 阻滞，并在转录和翻译水平上增加 p21WAF1 表达[2]。 Cell Proliferation Assay9-Hydroxyoctadecanoic acid 可以结合到人 HDAC1 蛋白三维模型的活性位点[1]。 Cell Line: HT29 cell Concentration: 100 μM Incubation Time: 24 h Result: Resulted in a significant inhibition of cell proliferation. Cell Cycle Analysis9-Hydroxyoctadecanoic acid 可以结合到人 HDAC1 蛋白三维模型的活性位点[1]。 Cell Line: HT29 cell Concentration: 100 μM Incubation Time: 24 h Result: Decreased S-phase activity by 50.2% compared with untreated controls, and the growth inhibition was associated with a strong arrest in G0/G1. Western Blot Analysis9-Hydroxyoctadecanoic acid 可以结合到人 HDAC1 蛋白三维模型的活性位点[1]。 Cell Line: HT29 cell Concentration: 100 μM Incubation Time: 24 h Result: Increased the expression of p21WAF1. RT-PCR9-Hydroxyoctadecanoic acid 可以结合到人 HDAC1 蛋白三维模型的活性位点[1]。 Cell Line: HT29 cell Concentration: 100 μM Incubation Time: 24 h Result: Induced p21WAF1 tanscript. |
| References |
| Molecular Formula | C18H36O3 |
|---|---|
| Molecular Weight | 300.48 |
| Exact Mass | 300.26600 |
| PSA | 57.53000 |
| LogP | 5.30330 |
| HS Code | 2918199090 |
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| Precursor 0 | |
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| DownStream 1 | |
CAS#:4114-74-3| HS Code | 2918199090 |
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| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
| 9-hydroxy-octadecanoic acid |
| 9-hydroxyoctadexanoic acid |
| 9-HSA |
| (+/-)-9-hydroxy-octadecanoic acid |
| (+/-)-9-Hydroxy-octadecansaeure |
| 9-hydroxystearic acid |