L-Cycloserine
Modify Date: 2026-07-03 21:10:09
L-Cycloserine structure
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Common Name | L-Cycloserine | ||
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| CAS Number | 339-72-0 | Molecular Weight | 102.09200 | |
| Density | 1.278 | Boiling Point | N/A | |
| Molecular Formula | C3H6N2O2 | Melting Point | 147ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of L-CycloserineL-cycloserine irreversibly inhibit GABA pyridoxal 5′-phosphate-dependent aminitransferase in E. coli, as well in the brains of various animals in a time-dependent manner, results in increased levels of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in vivo. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | L-cycloserine |
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| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | L-cycloserine irreversibly inhibit GABA pyridoxal 5′-phosphate-dependent aminitransferase in E. coli, as well in the brains of various animals in a time-dependent manner, results in increased levels of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in vivo. |
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| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.278 |
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| Melting Point | 147ºC |
| Molecular Formula | C3H6N2O2 |
| Molecular Weight | 102.09200 |
| Exact Mass | 102.04300 |
| PSA | 64.35000 |
| InChIKey | DYDCUQKUCUHJBH-REOHCLBHSA-N |
| SMILES | NC1CONC1=O |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
Synonym:L-4-Amino-3-Isoxalolidinone Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 339-72-0: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: white Odor: None reported. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 146 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: 10% Specific Gravity/Density: Molecular Formula: C3H6N2O2 Molecular Weight: 102.09 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, dust generation, excess heat, strong oxidants. Incompatibilities with Other Materials: Acids, strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 339-72-0: NY2976000 LD50/LC50: CAS# 339-72-0: Oral, mouse: LD50 = 2492 mg/kg. Carcinogenicity: L-Cycloserine - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 339-72-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 339-72-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 339-72-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R5 |
| Safety Phrases | 38-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | NY2976000 |
| HS Code | 2934999090 |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc... |
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Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat.
Exp. Physiol. 100 , 730-41, (2015) What is the central question of this study? The aim was to determine whether the accumulation of ceramide contributes to skeletal muscle insulin resistance in the JCR obese rat. What is the main findi... |
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Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
Bioorg. Med. Chem. 19 , 6409-18, (2011) The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati... |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 1-bromo-2,3,5,6-tetradeuterio-4-fluoro-benzene |
| 1-(5-(Hydroxymethyl)pyrimidin-2-yl)piperidin-4-ol |
| d4-4-bromofluorobenzene |
| cycloserine |
| 1-Bromo-4-fluorobenzene-d4 |
| 4-amino-isoxazolidin-3-one |
| D-4-amino-3-isoxazolidone |
| 4-fluoro-2,3,5,6-tetradeuterobromobenzene |
| L-CYCLOSERINE |
| MFCD00064324 |
| 4-Bromofluorobenzene-d4 |
| EINECS 206-427-0 |
| Cycloserine Impurity 1 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of L-cycloserine? |
| A: The English name of L-cycloserine is L-cycloserine. |
| Q: What English synonyms does L-cycloserine have? |
| A: English synonyms of L-cycloserine: 1-bromo-2,3,5,6-tetradeuterio-4-fluoro-benzene, 1-(5-(Hydroxymethyl)pyrimidin-2-yl)piperidin-4-ol, d4-4-bromofluorobenzene, cycloserine, 1-Bromo-4-fluorobenzene-d4, 4-amino-isoxazolidin-3-one, D-4-amino-3-isoxazolidone, 4-fluoro-2,3,5,6-tetradeuterobromobenzene, L-CYCLOSERINE, MFCD00064324, 4-Bromofluorobenzene-d4, EINECS 206-427-0, Cycloserine Impurity 1. |
| Q: What is the CAS number of L-cycloserine? |
| A: CAS number of L-cycloserine is 339-72-0. |
| Q: What is the SMILES notation of L-cycloserine? |
| A: SMILES notation of L-cycloserine is NC1CONC1=O. |
| Q: What is the melting point of L-cycloserine? |
| A: Melting point of L-cycloserine is 147ºC. |
| Q: What is the polar surface area (PSA) of L-cycloserine? |
| A: Polar surface area (PSA) of L-cycloserine is 64.35000. |
| Q: What are the storage conditions for L-cycloserine? |
| A: Storage conditions for L-cycloserine: 2-8°C. |
| Q: What is the molecular formula of L-cycloserine? |
| A: Molecular formula of L-cycloserine is C3H6N2O2. |
| Q: What is the InChIKey of L-cycloserine? |
| A: InChIKey of L-cycloserine is DYDCUQKUCUHJBH-REOHCLBHSA-N. |
| Q: What is the safety information for L-cycloserine? |
| A: Safety information for L-cycloserine: 38-36/37. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |