SMIFH2
Modify Date: 2024-01-11 19:46:49
SMIFH2 structure
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Common Name | SMIFH2 | ||
|---|---|---|---|---|
| CAS Number | 340316-62-3 | Molecular Weight | 377.21300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H9BrN2O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of SMIFH2SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM. |
| Name | (5E)-1-(3-Bromophenyl)-5-(2-furylmethylene)-2-thioxodihydro-4,6(1 H,5H)-pyrimidinedione |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C15H9BrN2O3S |
|---|---|
| Molecular Weight | 377.21300 |
| Exact Mass | 375.95200 |
| PSA | 98.13000 |
| LogP | 3.21430 |
| Storage condition | 2-8°C |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
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Control of myofibroblast differentiation by microtubule dynamics through a regulated localization of mDia2.
J. Biol. Chem. 288(22) , 15466-73, (2013) Myofibroblast differentiation plays a critical role in wound healing and in the pathogenesis of fibrosis. We have previously shown that myofibroblast differentiation is mediated by the activity of ser... |
| 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione |