Trachelogenin

Modify Date: 2024-01-05 00:24:48

Trachelogenin Structure
Trachelogenin structure
Common Name Trachelogenin
CAS Number 34209-69-3 Molecular Weight 388.41100
Density 1.300±0.06 g/cm3 Boiling Point N/A
Molecular Formula C21H24O7 Melting Point 144 ºC
MSDS N/A Flash Point N/A

 Use of Trachelogenin


Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1].

 Names

Name (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
Synonym More Synonyms

 Trachelogenin Biological Activity

Description Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1].
Related Catalog
References

[1]. Xi-Jing Qian, et al. Trachelogenin, a novel inhibitor of hepatitis C virus entry through CD81. J Gen Virol. 2016 May;97(5):1134-1144.

 Chemical & Physical Properties

Density 1.300±0.06 g/cm3
Melting Point 144 ºC
Molecular Formula C21H24O7
Molecular Weight 388.41100
Exact Mass 388.15200
PSA 94.45000
LogP 2.10730
Water Solubility Very slightly soluble (0.37 g/L) (25 ºC)

 Synonyms

Trachelogenin
(-)-Trachelogenin
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