4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide

Modify Date: 2026-07-17 19:13:46

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure
4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide structure
Common Name 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide
CAS Number 34258-79-2 Molecular Weight 330.35800
Density 1.497g/cm3 Boiling Point 490.5ºC at 760 mmHg
Molecular Formula C16H14N2O4S Melting Point N/A
MSDS N/A Flash Point 250.5ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.497g/cm3
Boiling Point 490.5ºC at 760 mmHg
Molecular Formula C16H14N2O4S
Molecular Weight 330.35800
Flash Point 250.5ºC
Exact Mass 330.06700
PSA 98.58000
LogP 3.85420
Index of Refraction 1.701
InChIKey PGUHYTRMLNGOQQ-UHFFFAOYSA-N
SMILES CN1C(C(=O)Nc2ccccc2)=C(O)c2ccccc2S1(=O)=O

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~57%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Koczian, Kristof; Voelgyi, Gergely; Koekoesi, Jozsef; Noszal, Bela Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1681 - 1690

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Lazer, Edward S.; Miao, Clara K.; Cywin, Charles L.; Sorcek, Ronald; Wong, Hin-Chor; Meng, Zhaoxing; Potocki, Ian; Hoermann, MaryAnn; Snow, Roger J.; Tschantz, Matt A.; Kelly, Terence A.; McNeil, Daniel W.; Coutts, Simon J.; Churchill, Laurie; Graham, Anne G.; David, Eva; Grob, Peter M.; Engel, Wolfhard; Meier, Hans; Trummlitz, Guenter Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 980 - 989

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Lazer, Edward S.; Miao, Clara K.; Cywin, Charles L.; Sorcek, Ronald; Wong, Hin-Chor; Meng, Zhaoxing; Potocki, Ian; Hoermann, MaryAnn; Snow, Roger J.; Tschantz, Matt A.; Kelly, Terence A.; McNeil, Daniel W.; Coutts, Simon J.; Churchill, Laurie; Graham, Anne G.; David, Eva; Grob, Peter M.; Engel, Wolfhard; Meier, Hans; Trummlitz, Guenter Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 980 - 989

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Lazer, Edward S.; Miao, Clara K.; Cywin, Charles L.; Sorcek, Ronald; Wong, Hin-Chor; Meng, Zhaoxing; Potocki, Ian; Hoermann, MaryAnn; Snow, Roger J.; Tschantz, Matt A.; Kelly, Terence A.; McNeil, Daniel W.; Coutts, Simon J.; Churchill, Laurie; Graham, Anne G.; David, Eva; Grob, Peter M.; Engel, Wolfhard; Meier, Hans; Trummlitz, Guenter Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 980 - 989

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Koczian, Kristof; Voelgyi, Gergely; Koekoesi, Jozsef; Noszal, Bela Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1681 - 1690

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Koczian, Kristof; Voelgyi, Gergely; Koekoesi, Jozsef; Noszal, Bela Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1681 - 1690

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Koczian, Kristof; Voelgyi, Gergely; Koekoesi, Jozsef; Noszal, Bela Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1681 - 1690

~%

4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide Structure

4-hydroxy-2-met...

CAS#:34258-79-2

Learn More
Literature: Lazer, Edward S.; Miao, Clara K.; Cywin, Charles L.; Sorcek, Ronald; Wong, Hin-Chor; Meng, Zhaoxing; Potocki, Ian; Hoermann, MaryAnn; Snow, Roger J.; Tschantz, Matt A.; Kelly, Terence A.; McNeil, Daniel W.; Coutts, Simon J.; Churchill, Laurie; Graham, Anne G.; David, Eva; Grob, Peter M.; Engel, Wolfhard; Meier, Hans; Trummlitz, Guenter Journal of Medicinal Chemistry, 1997 , vol. 40, # 6 p. 980 - 989

 Bioassay

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This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Inhibition of human Prostaglandin G/H synthase 2 at 0.1 ug/mL expressed as mean perce...
Source: ChEMBL
Target: Prostaglandin G/H synthase 2
External Id: CHEMBL763159
Name: Inhibition of human Prostaglandin G/H synthase 2 at 1 ug/mL expressed as mean percent...
Source: ChEMBL
Target: Prostaglandin G/H synthase 2
External Id: CHEMBL763160
Name: Inhibition of human Prostaglandin G/H synthase 2 at 10 ug/mL expressed as mean percen...
Source: ChEMBL
Target: Prostaglandin G/H synthase 2
External Id: CHEMBL763161
Name: Inhibition of human Prostaglandin G/H synthase 1 at 0.1 ug/mL expressed as mean perce...
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL765124
Name: Inhibition of human Prostaglandin G/H synthase 1 at 1 ug/mL expressed as mean percent...
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL765125
Name: Inhibition of human Prostaglandin G/H synthase 1 at 10 ug/mL expressed as mean percen...
Source: ChEMBL
Target: Prostaglandin G/H synthase 1
External Id: CHEMBL765126
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxanilide 1,1-dioxide
2-methyl-4-hydroxy-2H-benzothiazine-3-carboxanilide 1,1-dioxide
2H-1,2-Benzothiazine-3-carboxanilide,4-hydroxy-2-methyl-,1,1-dioxide
2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-phenyl-,1,1-dioxide
4-Hydroxy-2-methyl-N-phenyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
W7477

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the upstream materials of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: Related upstream materials(CAS) of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide: 24683-26-9;6639-62-9;35511-14-9;81-07-2;24683-20-3;128-44-9;24683-21-4;35511-15-0.
Q: What is the boiling point of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: Boiling point of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is 490.5ºC at 760 mmHg.
Q: What is the CAS number of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: CAS number of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is 34258-79-2.
Q: What is the molecular formula of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: Molecular formula of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is C16H14N2O4S.
Q: What is the polar surface area (PSA) of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: Polar surface area (PSA) of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is 98.58000.
Q: What English synonyms does 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide have?
A: English synonyms of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide: 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxanilide 1,1-dioxide, 2-methyl-4-hydroxy-2H-benzothiazine-3-carboxanilide 1,1-dioxide, 2H-1,2-Benzothiazine-3-carboxanilide,4-hydroxy-2-methyl-,1,1-dioxide, 2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-phenyl-,1,1-dioxide, 4-Hydroxy-2-methyl-N-phenyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, W7477.
Q: What is the LogP of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: LogP of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is 3.85420.
Q: What is the English name of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: The English name of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide.
Q: What is the InChIKey of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide?
A: InChIKey of 4-hydroxy-2-methyl-1,1-dioxo-N-phenyl-1λ6,2-benzothiazine-3-carboxamide is PGUHYTRMLNGOQQ-UHFFFAOYSA-N.
Q: What is the Chinese name of 34258-79-2?
A: Chinese name of 34258-79-2 is 34258-79-2.
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