Saccharin
Saccharin structure
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Common Name | Saccharin | ||
|---|---|---|---|---|
| CAS Number | 81-07-2 | Molecular Weight | 183.184 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 438.9±28.0 °C at 760 mmHg | |
| Molecular Formula | C7H5NO3S | Melting Point | 226-229 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 219.3±24.0 °C | |
Use of SaccharinSaccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1]. |
Summary: Saccharin (CAS number: 81-07-2) is a white crystalline solid with a molecular formula of C7H5NO3S and a molecular weight of 183.184. It is primarily used for producing pesticide intermediates, saccharin sodium, non-nutritive sweeteners, and intermediates for fungicides and herbicides. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | saccharin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1]. |
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| Related Catalog | |
| In Vitro | In vitro, saccharin (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner[1]. |
| In Vivo | In vivo, saccharin (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 438.9±28.0 °C at 760 mmHg |
| Melting Point | 226-229 °C(lit.) |
| Molecular Formula | C7H5NO3S |
| Molecular Weight | 183.184 |
| Flash Point | 219.3±24.0 °C |
| Exact Mass | 182.999008 |
| PSA | 71.62000 |
| LogP | 0.46 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.714 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility | 3.3 g/L (20 ºC) |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R40 |
| Safety Phrases | S24/25 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | DE4200000 |
| HS Code | 2925110000 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 4 | |
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| DownStream 10 | |
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CAS#:942047-62-3This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2925110000 |
|---|---|
| Summary | HS: 2925110000. benzo[d]isothiazol-3(2h)-one 1,1-dioxide. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:ab(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tarrif:9.0%. general tariff:90.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Nanocasting of carbon films with interdigitated bimodal three-dimensionally ordered mesopores by template-replica coassembly.
Langmuir 30(41) , 12411-20, (2014) Carbon films with interdigitated bimodal three-dimensionally ordered mesoporosity (ib3DOm) are realized by a scalable nanoreplication process that removes the common need plaguing hard-templating stra... |
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Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.
Bioorg. Med. Chem. Lett. 21 , 710-4, (2011) The catalytic activity and the inhibition of a new coral carbonic anhydrase (CA, EC 4.2.1.1), from the scleractinian coral Stylophora pistillata, STPCA-2, has been investigated. STPCA-2 has high catal... |
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Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii.
Bioorg. Med. Chem. 19 , 1847-51, (2011) A high activity α-carbonic anhydrase (CA, EC 4.2.1.1) has been purified from various tissues of the Antarctic seal Leptonychotes weddellii. The new enzyme, denominated lwCA, has a catalytic activity f... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 3-keto-2H,3H-1,2-benzisothiazole 1,1-dioxide |
| Sykose |
| T56 BSWMVJ |
| Saccharinose |
| Saccharol |
| 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide |
| Sacarina |
| UNII-FST467XS7D |
| Sweeta |
| Saxin |
| Saccharin |
| o-Benzoic acid sulfimide |
| EINECS 201-321-0 |
| Syncal |
| Kandiset |
| Natreen |
| 1,1-dioxo-benzo[d]isothiazol-3-one |
| 1,1-dioxo-1,2-benzisothiazol-3-one |
| 1,2-benzisothiazol-3(2H)-one-1,1-dioxide |
| 1,2-benzoisothiazol-3(2H)-one 1,1-dioxide |
| o-benzoic sulfimide |
| 1,2-benzisothiazol-3-one 1,1-dioxide |
| Gluside |
| Glycosin |
| Garantose |
| SACCHARINOL |
| MFCD00005866 |
| 1,2-Benzothiazol-3(2H)-one 1,1-dioxide |
| Glucid |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of saccharin? |
| A: Main uses of saccharin: Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties[1]. |
| Q: What is the LogP of saccharin? |
| A: LogP of saccharin is 0.46. |
| Q: What is the safety information for saccharin? |
| A: Safety information for saccharin: S24/25. |
| Q: What is the molecular weight of saccharin? |
| A: Molecular weight of saccharin is 183.184. |
| Q: What is the boiling point of saccharin? |
| A: Boiling point of saccharin is 438.9±28.0 °C at 760 mmHg. |
| Q: What is the English name of saccharin? |
| A: The English name of saccharin is saccharin. |
| Q: What is the polar surface area (PSA) of saccharin? |
| A: Polar surface area (PSA) of saccharin is 71.62000. |
| Q: How is the water solubility of saccharin? |
| A: Water solubility of saccharin: 3.3 g/L (20 ºC). |
| Q: What is the molecular formula of saccharin? |
| A: Molecular formula of saccharin is C7H5NO3S. |
| Q: What is the melting point of saccharin? |
| A: Melting point of saccharin is 226-229 °C(lit.). |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |