AG-7404

Modify Date: 2024-01-24 20:09:28

AG-7404 Structure
AG-7404 structure
Common Name AG-7404
CAS Number 343565-99-1 Molecular Weight 523.54
Density N/A Boiling Point N/A
Molecular Formula C26H29N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AG-7404


AG-7404 is an inhibitor of picornaviral 3C protease, with anti-poliovirus activity (EC50=0.080-0.674 μM). AG-7404 has synergy with V-073 (HY-104074) or BTA798 (HY-106254), and fully inhibits all V-073-resistant variants[1].

 Names

Name AG-7404

 AG-7404 Biological Activity

Description AG-7404 is an inhibitor of picornaviral 3C protease, with anti-poliovirus activity (EC50=0.080-0.674 μM). AG-7404 has synergy with V-073 (HY-104074) or BTA798 (HY-106254), and fully inhibits all V-073-resistant variants[1].
Related Catalog
References

[1]. Rhoden E,et al. Anti-poliovirus activity of protease inhibitor AG-7404, and assessment of in vitro activity in combination with antiviral capsid inhibitor compounds. Antiviral Res. 2013 May;98(2):186-91.  

 Chemical & Physical Properties

Molecular Formula C26H29N5O7
Molecular Weight 523.54