(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one structure
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Common Name | (4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one | ||
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CAS Number | 34371-14-7 | Molecular Weight | 132.11500 | |
Density | 1.438g/cm3 | Boiling Point | 395.3ºC at 760mmHg | |
Molecular Formula | C5H8O4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 179.1ºC |
Name | 2-deoxy-D-ribono-1,4-lactone |
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Synonym | More Synonyms |
Density | 1.438g/cm3 |
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Boiling Point | 395.3ºC at 760mmHg |
Molecular Formula | C5H8O4 |
Molecular Weight | 132.11500 |
Flash Point | 179.1ºC |
Exact Mass | 132.04200 |
PSA | 66.76000 |
Index of Refraction | 1.521 |
Storage condition | 2-8°C |
Hazard Codes | Xi |
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RIDADR | NONH for all modes of transport |
HS Code | 2932209090 |
HS Code | 2932209090 |
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Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions.
Mutat. Res. Fundam. Mol. Mech. Mutagen. 762 , 32-9, (2014) A signature of ionizing radiation is the induction of DNA clustered damaged sites. Non-double strand break (DSB) clustered damage has been shown to compromise the base excision repair pathway, extendi... |
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Analysis of base excision DNA repair of the oxidative lesion 2-deoxyribonolactone and the formation of DNA-protein cross-links.
Meth. Enzymol. 408 , 48-64, (2006) DNA base lesions arising from oxidation or alkylation are processed primarily by the base excision repair pathway (BER). The damaged bases are excised by DNA N-glycosylases, which generate apurinic/ap... |
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Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone.
J. Am. Chem. Soc. 134(19) , 8090-3, (2012) Oxidized abasic sites such as 2-deoxyribonolactone (L) are produced in DNA by a variety of oxidizing agents, including potent cytotoxic antitumor natural products. 2-Deoxyribonolactone is labile under... |
2-deoxy-D-erythro-pentono-1,5-lactone |
(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-one |
2-deoxy-D-ribonolactone |
2-Deoxy-ribono-1,4-lactone |
Deoxyribonolactone |
2-Deoxyribonolactone |
2-Deoxy-D-ribono-1,4-lactone |
2-Deoxy-D-ribonic-1,4-lactone |