(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

Modify Date: 2025-08-23 15:08:50

(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one structure	Common Name	(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
	CAS Number	34371-14-7	Molecular Weight	132.11500
	Density	1.438g/cm3	Boiling Point	395.3ºC at 760mmHg
	Molecular Formula	C₅H₈O₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	179.1ºC

Name	2-deoxy-D-ribono-1,4-lactone
Synonym	More Synonyms

Density	1.438g/cm3
Boiling Point	395.3ºC at 760mmHg
Molecular Formula	C₅H₈O₄
Molecular Weight	132.11500
Flash Point	179.1ºC
Exact Mass	132.04200
PSA	66.76000
Index of Refraction	1.521
Storage condition	2-8°C

MSDS(Chinese)

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
HS Code	2932209090

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions.

Mutat. Res. Fundam. Mol. Mech. Mutagen. 762 , 32-9, (2014)

A signature of ionizing radiation is the induction of DNA clustered damaged sites. Non-double strand break (DSB) clustered damage has been shown to compromise the base excision repair pathway, extendi...

Analysis of base excision DNA repair of the oxidative lesion 2-deoxyribonolactone and the formation of DNA-protein cross-links.

Meth. Enzymol. 408 , 48-64, (2006)

DNA base lesions arising from oxidation or alkylation are processed primarily by the base excision repair pathway (BER). The damaged bases are excised by DNA N-glycosylases, which generate apurinic/ap...

Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone.

J. Am. Chem. Soc. 134(19) , 8090-3, (2012)

Oxidized abasic sites such as 2-deoxyribonolactone (L) are produced in DNA by a variety of oxidizing agents, including potent cytotoxic antitumor natural products. 2-Deoxyribonolactone is labile under...

2-deoxy-D-erythro-pentono-1,5-lactone

(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-one

2-deoxy-D-ribonolactone

2-Deoxy-ribono-1,4-lactone

Deoxyribonolactone

2-Deoxyribonolactone

2-Deoxy-D-ribono-1,4-lactone

2-Deoxy-D-ribonic-1,4-lactone