(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one

Modify Date: 2024-01-02 17:22:17

(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one Structure
(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one structure
Common Name (4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one
CAS Number 34371-14-7 Molecular Weight 132.11500
Density 1.438g/cm3 Boiling Point 395.3ºC at 760mmHg
Molecular Formula C5H8O4 Melting Point N/A
MSDS Chinese USA Flash Point 179.1ºC

 Names

Name 2-deoxy-D-ribono-1,4-lactone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.438g/cm3
Boiling Point 395.3ºC at 760mmHg
Molecular Formula C5H8O4
Molecular Weight 132.11500
Flash Point 179.1ºC
Exact Mass 132.04200
PSA 66.76000
Index of Refraction 1.521
Storage condition 2-8°C

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 2932209090

 Synthetic Route

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles31

More Articles
Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions.

Mutat. Res. Fundam. Mol. Mech. Mutagen. 762 , 32-9, (2014)

A signature of ionizing radiation is the induction of DNA clustered damaged sites. Non-double strand break (DSB) clustered damage has been shown to compromise the base excision repair pathway, extendi...

Analysis of base excision DNA repair of the oxidative lesion 2-deoxyribonolactone and the formation of DNA-protein cross-links.

Meth. Enzymol. 408 , 48-64, (2006)

DNA base lesions arising from oxidation or alkylation are processed primarily by the base excision repair pathway (BER). The damaged bases are excised by DNA N-glycosylases, which generate apurinic/ap...

Histone-catalyzed cleavage of nucleosomal DNA containing 2-deoxyribonolactone.

J. Am. Chem. Soc. 134(19) , 8090-3, (2012)

Oxidized abasic sites such as 2-deoxyribonolactone (L) are produced in DNA by a variety of oxidizing agents, including potent cytotoxic antitumor natural products. 2-Deoxyribonolactone is labile under...

 Synonyms

2-deoxy-D-erythro-pentono-1,5-lactone
(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-one
2-deoxy-D-ribonolactone
2-Deoxy-ribono-1,4-lactone
Deoxyribonolactone
2-Deoxyribonolactone
2-Deoxy-D-ribono-1,4-lactone
2-Deoxy-D-ribonic-1,4-lactone